A cortical cystic epileptogenic lesion: tanycytic ependymoma

Rigante, Luigi; Novello, Mariangela; Massimi, Luca; Caldarelli, Massimo

doi:10.1007/s13760-012-0157-3

Cited by 9 publications

(8 citation statements)

References 4 publications

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“…Compared to conventional ependymoma, supratentorial CE is rare. Including our 11 cases, there are only 45 cases, in which 24 cases are WHO grade II CEs and 21 cases are anaplastic CEs (WHO Grade III) (Tables and ) . For patients with low‐grade CEs, the median age is 20 years ranging from 2 to 63 years.…”

Section: Discussionmentioning

confidence: 99%

“…For patients with low‐grade CEs, the median age is 20 years ranging from 2 to 63 years. The male‐to‐female ratio is 1:1 . For patients with anaplastic CEs, the median age is 33 years, ranging from 1 to 70 years old.…”

Section: Discussionmentioning

confidence: 99%

“…Including our 11 cases, there are only 45 cases, in which 24 cases are WHO grade II CEs and 21 cases are anaplastic CEs (WHO Grade III) (Tables 3 and 4). 4,5,[8][9][10]12,13,[16][17][18][19][20][21][22][23][24] For patients with low-grade CEs, the median age is 20 years ranging from 2 to 63 years. The male-tofemale ratio is 1:1.…”

Section: Discussionmentioning

confidence: 99%

“…The male-tofemale ratio is 1:1. 4,5,[8][9][10][12][13][14][15]17,18,[20][21][22]24 For patients with anaplastic CEs, the median age is 33 years, ranging from 1 to 70 years old. The male-to-female ratio is 1:1.1.…”

Section: Discussionmentioning

confidence: 99%

“…Cortical ependymomas (CEs) are designated as supratentorial ependymomas that are primarily located in the cerebral cortex. There are only 34 cases of CEs in the literature . The majority of publications are case reports.…”

Section: Introductionmentioning

confidence: 99%

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Supratentorial cortical ependymoma: Case series and review of the literature

Liu

et al. 2013

Neuropathology

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Supratentorial cortical ependymoma (CE), a rare type of ependymoma, is located in the superficial cortex. We reported 11 patients (six female and five male) with CE. The age of the patients ranged from 2 to 63 years old with a median age of 47 years at the time of diagnosis. On MRI, enhancement was noted in all cases with solid appearance in six cases, and solid and cystic appearance in five cases. The frontal and parietal regions were the most common locations for CE. On histology, two were low-grade (WHO grade II) and nine were WHO grade III anaplastic ependymomas. Some tumors exhibited clear cell, spindle (tanycytic) and giant cell morphologies, as well as the classic ependymoma morphology. Dura-based tumor nodules and even tumor dissemination along the dura can be seen in CEs. Low grade CEs have a higher likelihood to present with seizures, a lower likelihood to cause brain edema, tumor recurrence and lower mortality than anaplastic ependymomas. While difficult, anaplastic CEs may be distinguished from glioblastoma by a clear interface between tumor and adjacent brain tissue, relative uniformity of tumor cell nuclei and immunopositivity for epithelial membrane antigen and/or CD99. As is the case for ependymomas in general, gross total resection is still the treatment of choice for CEs.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Supratentorial cortical ependymoma: Case series and review of the literature

Liu

et al. 2013

Neuropathology

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The clinical features and surgical outcomes of intracranial tanycytic ependymomas: a single-institutional experience

et al. 2017

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Tanycytic ependymoma is a rare subtybe of ependymoma with a predilection for the spinal cord and intracranial tanycytic ependymoma is thus extremely rare. Most studies on intracranial tanycytic ependymomas included only one or two cases. Here we report nine patients with pathologically confirmed intracranial tanycytic ependymomas. The clinical characteristics, including radiological and histological examination, operative records, and prognoses were reviewed. The case series included six male and three female patients with an average age of 19.3 years. Tumors were located in the lateral ventricle (3/9), the fourth ventricle (2/9), and the supratentorial extraventricle (4/9). Gross total resection (GTR) of the tumor was achieves in seven cases, and subtotal resection (STR) was achieved in the other two cases. One patient died 21 months after discharge. The left eight patients showed improved symptoms after surgery, and no tumor recurrence was found in these cases during the follow-up. It seems that intracranial tanycytic ependymoma has the best long-term prognosis compared to the other two subtypes of ependymoma. According to our experience, we recommend surgery including GTR and STR followed by radiotherapy for patients with intracranial tanycytic ependymomas.

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