A Consideration of the Treatment of Elderly Primigravidae

Effect of Aging on Fertility and Pregnancy

“…Some previous studies have suggested longer labors for older primiparas. 64,70,71 This risk in primigravidas is supported by the recent well controlled study by Berkowitz et al, 66 who found that the risk for having prolonged second stage of labor (i.e., lasting more than 2 hours) was higher in the 30-to 34-year-old and older than 35 years groups. For multiparas there is good evidence that the second stage of labor is prolonged with increasing age.…”

Obstetric and neonatal risk of pregnancies after assisted reproductive technology: a matched control study

“…Women who achieve pregnancy after ART are usually older than average; the proportion of elderly primigravid patients over the age of 35 years is fairly high. It is generally accepted that older women are more prone to obstetric problems (20–22), although some studies confirm this only in part (23). Further pregnancies among older women after ART do not have a worse outcome than that for spontaneously conceived pregnancies among women of the same age (24).…”

Effect of arsenite, maternal age, and embryonic sex on spina bifida, exencephaly, and resorption rates in the splotch mouse

“…Many human pregnancy outcomes are affected by maternal age, including maternal risk, fetal risk, and fertility risk. The age at which maternal age is considered “advanced” is highly variable, with age 35 as the most frequently used standard (MacDonald and MacLennon, 1960; Mansfield, 1986; Cunningham et al, 1997; Milunsky, 1998). For a pregnant woman 35 years and older, there is an increased risk for gestational diabetes and toxemia (Romero‐Maldonado et al, 2002).…”