A Conceptual Model for Detecting Interactions among Medical Recommendations in Clinical Guidelines

Generalizing the Detection of Internal and External Interactions in Clinical Guidelines

“…We start by addressing realistic but simplified case studies, and add more complexity according to the lessons learned in each iteration. Therefore, this paper is the continuation of earlier work reported in (Zamborlini et al, 2014a;Zamborlini et al, 2014b;Zamborlini et al, 2015b;Zamborlini et al, 2015a). In this series of work, we investigated (i) what knowledge is required to represent and reason about CGs (rather than how to acquire such knowledge), particularly for supporting the multimorbidity issue; (ii) how it can be formalized; (iii) how it can be implemented using Semantic Web technologies, so that (iv) we can exploit the medical knowledge available as Linked Open Data (LOD).…”

“…The following FOL rule defines the derivable relation regulates while the interactions are defined in the next subsections. Some interaction types have a cumulative behavior, like Repeated Action and Alternative Actions (introduced in (Zamborlini et al, 2014b)). For example, if three norms recommend the administration of aspirin, there should be one single interaction of type Repeated Action among them, rather than three different interactions among pairs of them.…”

“…Explicit description of local constraints and impact of recommendations is considered an important source of information for increased reasoning capabilities and improved explanation of conflicts in (Bonacin et al, 2013). The model described in (Zamborlini et al, 2014a) introduced clinical recommendations as governing care actions that cause state transitions; an extended version of this model presented in (Zamborlini et al, 2014b) defines different ways in which recommendation can interact according to the referred actions and transitions. The implementation and evaluation of the model using Semantic Web languages was proposed by us in (Zamborlini et al, 2015b).…”

Temporal detection and analysis of guideline interactions

“…Several approaches to the treatment of comorbidities with CIGs have been recently proposed. Among them, the approach in [16] is the most similar to ours. It provides a conceptual model for medical actions and detects interactions using such a model and first order logic (FOL) rules.…”

Temporal reasoning techniques for the analysis of interactions in the treatment of comorbid patients

“…Among them, the approach in [15] is the most similar to ours. It provides a conceptual model for medical actions and detects interactions using such a model and rules.…”