A comprehensive study of autonomic dysfunction in the fibromyalgia patients

Kulshreshtha, Poorvi; Gupta, Rajiva; Yadav, Raj Kumar; Bijlani, R L; Deepak, Kishore Kumar

doi:10.1007/s10286-011-0150-6

Cited by 46 publications

(85 citation statements)

References 19 publications

(19 reference statements)

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“…* Correlation is significant at the 0.05 level. the frequency-domain [3,4,8,32]. In the review by Meeus et al [33], a similar result was observed but in a meta-analysis from 2009 by Tak et al [34] this difference did not reach significance for a subgroup of FM patients although the difference was significant for a compound group with functional somatic disorders.…”

Section: Hrvmentioning

confidence: 47%

“…HRV is measured for several different parameters and in individuals presenting FM. These parameters are deviant and lower in comparison with the HRV observed in healthy reference persons [3,6,7]. Parasympathetic hypoactivity in women with FM may be detected through HRV measurements and has been associated with poor sleep quality [5,8] and chronic fatigue syndrome [9].…”

Section: Introductionmentioning

confidence: 98%

“…Several studies have shown changes in the autonomous nervous system (ANS) of individuals presenting FM that are manifested as sympathetic hyperactivity and parasympathetic hypoactivity [3,4]. No specific test may solely measure autonomic function but the registration of heart rate variability (HRV) is a non-invasive method that detects changes in the parasympathetic branch of ANS and in the balance between sympathetic and parasympathetic activity.…”

Section: Introductionmentioning

confidence: 99%

“…Physical therapists may contribute this finesse and guide persons with FM to activation self-management [12,13]. In healthy subjects, HRV has been used to optimize exercise load and increased knowledge about HRV in FM could optimize physical therapy exercise interventions [3].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Physiological Adaptation in Women Presenting Fibromyalgia: Comparison with Healthy Controls

Lange¹,

Mannerkorpi²,

Cider³

et al. 2017

Clin Exp Psychol

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Objective: To compare the heart rate variability (HRV) before and after a sub-maximal exercise test in women with fibromyalgia (FM) and to compare the result to matched controls. Additionally, to compare heart rate (HR) before, during and after the sub-maximal exercise test.Methods: Twenty-four women with FM and 26 controls performed a sub-maximal exercise test. HRV was registered for 5 minutes at rest before and after the exercise test. HR was registered at baseline, during the exercise test and at recovery. Results:The HRV of the healthy group was statistically different from the exercise test but the women with FM showed no such difference. HR was significantly higher among the women with FM than in the healthy group at baseline and up to 75W but lower at peak (138/152 bpm, p<0.008). In women with FM HR during exercise (HR2) was predicted by heart rate recovery (HRR20) and physical exertion (RPE2). HRR20 and RPE2 accounted for 0.465 of the variance (p=0.006) in HR2. In healthy women HR2 correlated with HRR20 and negatively with physical activity (PhA). In the reference group HRR20 and PhA accounted for 0.448 (p=0.002) of the variance HR. Conclusion:The HRV in women with FM show less adjustment of the ANS while not being significantly affected by submaximal exercise as healthy women. In healthy women heart rate during the test was negatively related to PhA. In women with FM exertion seems to replace an effect from exercise on physiological adaptation. FM may entail imperceptible extraction of power from PhA while under load. Links to FM pain will be discussed.Women with FM seem to rate exertion "Very hard" on lower workload and HR than healthy women. The physiotherapeutic methodology for measuring HRV with basic HR monitors should be improved before it can be recommended for clinical use.

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