A Comprehensive Literature Review of the Pelvis and the Lower Extremity FE Human Models under Quasi-static Conditions

Al-Dirini, Rami; Thewlis, Dominic; Paul, Gunther

doi:10.3233/wor-2012-1039-4218

Cited by 14 publications

(10 citation statements)

References 19 publications

(63 reference statements)

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“…As the knee geometries of the subjects were not available, a reference geometry was used. The right lower limb of the Visible Human Project (VHP) [20] was selected as the extended data are free of charge and were used as reference geometry in numerous studies [21, 22]. The anatomical points used to obtain the SCS of both authors' and standardised conventions were identified on the VHP subject geometry.…”

Section: Methodsmentioning

confidence: 99%

Kinematics of the Normal Knee during Dynamic Activities: A Synthesis of Data from Intracortical Pins and Biplane Imaging

Gasparutto

Moissenet

Lafon

et al. 2017

Applied Bionics and Biomechanics

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Few studies have provided in vivo tibiofemoral kinematics of the normal knee during dynamic weight-bearing activities. Indeed, gold standard measurement methods (i.e., intracortical pins and biplane imaging) raise ethical and experimental issues. Moreover, the conventions used for the processing of the kinematics show large inconsistencies. This study aims at synthesising the tibiofemoral kinematics measured with gold standard measurement methods. Published kinematic data were transformed in the standard recommended by the International Society of Biomechanics (ISB), and a clustering method was applied to investigate whether the couplings between the degrees of freedom (DoFs) are consistent among the different activities and measurement methods. The synthesised couplings between the DoFs during knee flexion (from 4° of extension to −61° of flexion) included abduction (up to −10°); internal rotation (up to 15°); and medial (up to 10 mm), anterior (up to 25 mm), and proximal (up to 28 mm) displacements. These synthesised couplings appeared mainly partitioned into two clusters that featured all the dynamic weight-bearing activities and all the measurement methods. Thus, the effect of the dynamic activities on the couplings between the tibiofemoral DoFs appeared to be limited. The synthesised data might be used as a reference of normal in vivo knee kinematics for prosthetic and orthotic design and for knee biomechanical model development and validation.

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Section: Methodsmentioning

confidence: 99%

Kinematics of the Normal Knee during Dynamic Activities: A Synthesis of Data from Intracortical Pins and Biplane Imaging

Gasparutto

Moissenet

Lafon

et al. 2017

Applied Bionics and Biomechanics

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“…12, with the lowest score of 3/12 and the highest score of 12/12 (SD ± 2.32). According to Al-Dirini et al, the average CASP score for all the studies indicates an acceptable level of relevance and quality (32). In this review, most of the RCTs (n=12) and cohort studies (n=17) had an acceptable level of relevance and quality.The CASP quality assessment also demonstrated that most of the included RCTs (n=15) didnot have a positive value for the last item of the CASP RCT checklist (the value of the studied intervention compared to the existing interventions).…”

mentioning

confidence: 69%

“…(29) However, different reviews have used the CASP total scores to assess the quality of included studies. (30)(31)(32) Following the approach used in these studies, each item evaluated was awarded the following qualitative scores: "Yes" (1 point), "No" (0 points), or "Cannot tell" (0 points) to obtain the overall CASP scores.…”

Section: Quality Assessmentmentioning

confidence: 99%

Interventions developed to reduce secondary care utilisation in patients with type 2 diabetes mellitus: a narrative review

Khayyat

Walters

Whittlesea³

et al. 2022

International Journal of Pharmacy Practice

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Objectives To identify, describe and critically appraise the quality of studies of interventions developed to reduce the rate of secondary care utilisation and investigate interventions’ impact on patients with type 2 diabetes mellitus (T2DM). Method Using a systematic approach, five databases were searched between 01 January 1995 and 01 February 2021 (MEDLINE, EMBASE, PsycINFO, CINAHL and Cochrane database). Inclusion criteria were studies (published in English) in adults with T2DM offered intervention(s) involving medicines/services/educational programmes in any country or setting, with investigated outcomes including the rate of hospital admission/re-admission/accident and emergency visits. Validated tools were used to assess the quality and accuracy of reporting the interventions. A narrative synthesis was used to frame the findings. Key findings A total of 4670 papers were identified, which yielded a final 53 studies after screening against the inclusion criteria. Identified interventions were complex interventions (n = 21) including at least two interventions (e.g. improving medication adherence and patient education), medication management (n = 15), patient education programmes (n = 8), lifestyle interventions (n = 5) and other interventions (n = 4; e.g. dental care). After assessing for quality and effectiveness of interventions, 15 studies remained; 7 were medication management interventions (e.g. use of insulin pen) and 8 were complex interventions (e.g. pharmaceutical care and telehealth systems). Complex interventions showed significant improvement in clinical outcomes and reduction in secondary care utilisation. Conclusions This narrative review identified potential elements of an effective complex intervention to reduce healthcare utilisation in patients with T2DM. These results could inform the development of interventions to be tested for feasibility, before piloting to assess for outcomes that improve diabetic care, reduce diabetes-related complications and minimise healthcare utilisation.

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“…The units for the PK parameters were standardized for all the studies to keep the data consistent for the comparison of the results. To assess the methodological quality of Randomized Controlled Trials (RCTs), a modified Jaded scale 21 and the Critical Appraisal Scale Programme (CASP) tool 22 were used in this review. To assess the risk of bias Cochrane collaboration tool for risk bias assessment was used 23 …”

Section: Methodsmentioning

confidence: 99%

Clinical pharmacokinetics of nadolol: A systematic review

Kalsoom

Zamir

Rehman

et al. 2022

Clinical Pharmacy Therapeu

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What is known and objective: Nadolol is a non-selective beta-adrenergic antagonist that is used for the treatment of hypertension and angina. The primary route for its administration is oral. It is given once daily as it has a longer half-life (t½). The purpose of conducting this systematic review is to provide a comprehensive view of all the available pharmacokinetic (PK) data on nadolol in humans. This review aimed to systematically collate and analyze publish data on the clinical PK of nadolol in humans and this can be beneficial for the clinicians in dosage adjustments.Methods: Two electronic databases PubMed and Google Scholar were used for conducting a systematic literature search. All the relevant articles containing PK data of nadolol in humans were retrieved. A total of 1275 articles were searched from both databases and after applying eligibility criteria finally, 22 articles were included for conducting the systematic review.Results and discussion: The area under the plasma concentration curve (AUC) and maximum plasma concentration (C max ) of nadolol increased in a dose-dependent manner. The t½ of nadolol was increased to double (18.2-68.6 h) in the patients with chronic kidney disease while the serum t½ became shorter (3.2-4.3 h) when administered to the children. The bioavailability of nadolol was greatly reduced by the coadministration of green tea. Nadolol can be effectively removed by hemodialysis. It undergoes enterohepatic circulation thus activated charcoal decreased its bioavailability.What is new and conclusion: Since, there is no previous report of a systematic review on the PK of nadolol, the current review encompasses all the relevant published articles on nadolol in humans. The analysis and understanding of PK parameters (AUC, C max , and t½) of nadolol may be helpful in the development and evaluation of PK models.

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A Comprehensive Literature Review of the Pelvis and the Lower Extremity FE Human Models under Quasi-static Conditions

Cited by 14 publications

References 19 publications

Kinematics of the Normal Knee during Dynamic Activities: A Synthesis of Data from Intracortical Pins and Biplane Imaging

Kinematics of the Normal Knee during Dynamic Activities: A Synthesis of Data from Intracortical Pins and Biplane Imaging

Interventions developed to reduce secondary care utilisation in patients with type 2 diabetes mellitus: a narrative review

Clinical pharmacokinetics of nadolol: A systematic review

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