A Competitive Bio-Barcode Amplification Immunoassay for Small Molecules Based on Nanoparticles

Du, Pengfei; Jin, Maojun; Chen, Ge; Zhang, Chan; Jiang, Zejun; Zhang, Yanxin; Pan, Zhizhong; She, Yongxin; Jin, Fen; Shao, Hua; Wang, Shanshan; Zheng, Lirong; Wang, Jing

doi:10.1038/srep38114

Cited by 43 publications

(20 citation statements)

References 35 publications

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“…There are five types of labeled immunoassays: radioimmunoassay (RIA), fluorescence immunoassay (FIA), chemiluminescence immunoassay (CLIA), enzyme‐linked immunoassay (ELISA), and bio‐barcode immunoassay, and they are employed as biosensing analytical tools [194,195]. Among them, the enzyme‐based biosensors for analyzing pesticides and veterinary drugs have attracted tremendous interest owing to their fast response, reliability, selectivity, and high sensitivity [196]. A list of representative pesticides and veterinary drugs, which were determined by various immunoassays, is presented in Table 3 .…”

Section: Immunoassays For Detecting Pesticides and Veterinary Drugsmentioning

confidence: 99%

Onsite/on‐field analysis of pesticide and veterinary drug residues by a state‐of‐art technology: A review

Rahman

Lee

et al. 2021

J of Separation Science

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Pesticides and veterinary drugs are generally employed to control pests and insects in crop and livestock farming. However, remaining residues are considered potentially hazardous to human health and the environment. Therefore, regular monitoring is required for assessing and legislation of pesticides and veterinary drugs. Various approaches to determining residues in various agricultural and animal food products have been reported. Most analytical methods involve sample extraction, purification (cleanup), and detection. Traditional sample preparation is time‐consuming labor‐intensive, expensive, and requires a large amount of toxic organic solvent, along with high probability for the decomposition of a compound before the analysis. Thus, modern sample preparation techniques, such as the quick, easy, cheap, effective, rugged, and safe method, have been widely accepted in the scientific community for its versatile application; however, it still requires a laboratory setup for the extraction and purification processes, which also involves the utilization of a toxic solvent. Therefore, it is crucial to elucidate recent technologies that are simple, portable, green, quick, and cost‐effective for onsite and infield residue detections. Several technologies, such as surface‐enhanced Raman spectroscopy, quantum dots, biosensing, and miniaturized gas chromatography, are now available. Further, several onsite techniques, such as ion mobility–mass spectrometry, are now being upgraded; some of them, although unable to analyze field sample directly, can analyze a large number of compounds within very short time (such as time‐of‐flight and Orbitrap mass spectrometry). Thus, to stay updated with scientific advances and analyze organic contaminants effectively and safely, it is necessary to study all of the state‐of‐art technology.

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Section: Immunoassays For Detecting Pesticides and Veterinary Drugsmentioning

confidence: 99%

Onsite/on‐field analysis of pesticide and veterinary drug residues by a state‐of‐art technology: A review

Rahman

Lee

et al. 2021

J of Separation Science

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“…The method showed a linear range of 0.01–20 μg/L, and the LOD was 6 ng/L. Du et al [99] , [100] established a bio-barcode competitive immunoassay method based on a microplate platform. By designing different DNA strands, the detection of triazophos pesticides was realized.…”

Section: Single-molecule Single-residue Detectionmentioning

confidence: 99%

Bio-barcode detection technology and its research applications: A review

Wang

Jin

Chen

et al. 2019

Journal of Advanced Research

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“…9). The barcode DNA isolated from AuNPs in the tube and detected by real-time PCR (Du P. et al, 2016) Fig. 8.…”

Section: Light Scatteringmentioning

confidence: 99%

Optical Bio-barcode Nanobiosensors

Yalcinkaya

Hamsho

2019

Uluslararası Muhendislik Arastirma Ve Gelistirme Dergisi

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Nanobiosensors are at the core of multidisciplinary research worldwide, from textiles to medicine, from space research to marine. The field of optical nanobiosensors has a special importance within this growing area over the last quarter of the century. Various forms of optical detection methods have been used in a wide spectrum of applications. Practical applications are intentionally given to help clinicians and laboratory employees in terms of materials, compositions, and protocols of use. This tutorial review includes recent efforts in the use of nanoparticle-based bio-barcode analysis to detect a target molecule by focusing on optical techniques.The optical sensing part defines fluorescence, real-time PCR, colorimetric, luminescence, surface plasmon and electrophoresis resonance systems. Finally, applications have been summarized in the detection of pathogenic microorganisms, clinical analysis, pesticides and toxicants in the environmental area and in food products.

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A Competitive Bio-Barcode Amplification Immunoassay for Small Molecules Based on Nanoparticles

Cited by 43 publications

References 35 publications

Onsite/on‐field analysis of pesticide and veterinary drug residues by a state‐of‐art technology: A review

Onsite/on‐field analysis of pesticide and veterinary drug residues by a state‐of‐art technology: A review

Bio-barcode detection technology and its research applications: A review

Optical Bio-barcode Nanobiosensors

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