Bio-barcode detection technology and its research applications: A review

Wang, Yuanshang; Jin, Maojun; Chen, Ge; Cui, Xueyan; Zhang, Yudan; Li, Mingjie; Liao, Yun; Zhang, Xiuyuan; Qin, Guoxin; Yan, Feiyan; El‐Aty, A.M. Abd; Wang, Jing

doi:10.1016/j.jare.2019.04.009

Cited by 35 publications

(12 citation statements)

References 110 publications

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“…Upon interaction with the target DNA, a sandwich complex between the magnetic microparticle and AuNPs probes is formed. The sandwich is then separated by the magnet followed by thermal dehybridization to release the free bar-code DNA, enabling detection and quantification of the target [ 101 , 102 ].…”

Section: Biological Application Of Aunpsmentioning

confidence: 99%

Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review

et al. 2021

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The medical properties of metals have been explored for centuries in traditional medicine for the treatment of infections and diseases and still practiced to date. Platinum-based drugs are the first class of metal-based drugs to be clinically used as anticancer agents following the approval of cisplatin by the United States Food and Drug Administration (FDA) over 40 years ago. Since then, more metals with health benefits have been approved for clinical trials. Interestingly, when these metals are reduced to metallic nanoparticles, they displayed unique and novel properties that were superior to their bulk counterparts. Gold nanoparticles (AuNPs) are among the FDA-approved metallic nanoparticles and have shown great promise in a variety of roles in medicine. They were used as drug delivery, photothermal (PT), contrast, therapeutic, radiosensitizing, and gene transfection agents. Their biomedical applications are reviewed herein, covering their potential use in disease diagnosis and therapy. Some of the AuNP-based systems that are approved for clinical trials are also discussed, as well as the potential health threats of AuNPs and some strategies that can be used to improve their biocompatibility. The reviewed studies offer proof of principle that AuNP-based systems could potentially be used alone or in combination with the conventional systems to improve their efficacy.

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Section: Biological Application Of Aunpsmentioning

confidence: 99%

Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review

et al. 2021

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“…Additionally, while there are numerous biological colorimetric assays that reveal the presence (but not the amount) of a food contaminant such as Listeria and Salmonella , these assays must be combined with quantitative polymerase chain reaction (qPCR) techniques − to amplify and quantify bacterial presence in food. A variety of review articles have been published describing the advantages and disadvantages of qPCR assays in food safety. − Here, we will focus on the use of traditional UV–visible spectroscopy for the detection of organic contaminants and leveraging UV–vis extinction spectroscopy for NP-enabled detection schemes.…”

Section: Uv–visible Spectroscopy/colorimetric Techniquesmentioning

confidence: 99%

Sensing Food Contaminants: Advances in Analytical Methods and Techniques

et al. 2020

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“…The bio-barcode assay (BCA) was established to simultaneously detect multiple targets in a single run [ 10 ] . It is based on the relationship between the DNA barcoding strand and the target protein, which the bio-barcoding technology utilizes to perform multi-residue detection of macromolecular compounds.…”

Section: Introductionmentioning

confidence: 99%