A Comparison of the Original Chronic Respiratory Questionnaire With a Standardized Version

̈nemann, Holger J. Schu; Griffith, Lauren; Jaeschke, Roman; Goldstein, Roger; Stubbing, David; Austin, Peggy; Guyatt, Gordon

doi:10.1378/chest.124.4.1421

Cited by 88 publications

(85 citation statements)

References 21 publications

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“…Effect sizes of 0.5 were found with a CRQ dyspnoea score of 0.61 units, CRQ fatigue score of 0.67 units, CRQ emotional function score of 0.60 units and CRQ mastery score of 0.60 units [116,447].…”

Section: Statistical Mid Estimatementioning

confidence: 94%

See 1 more Smart Citation

Outcomes for COPD pharmacological trials: from lung function to biomarkers

Cazzola¹,

MacNee²,

Martínez³

et al. 2008

European Respiratory Journal

747

566

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Section: Statistical Mid Estimatementioning

confidence: 94%

“…In a study of the effects of pulmonary rehabilitation, the SGRQ was compared with another disease-specific health status measure, the CRQ [447]. Using the MID for the CRQ, it was estimated that the MID for SGRQ total score (95% CI) was 3.05 (0.39-5.71) units.…”

Section: External Measure-based Midmentioning

confidence: 99%

Outcomes for COPD pharmacological trials: from lung function to biomarkers

Cazzola¹,

MacNee²,

Martínez³

et al. 2008

European Respiratory Journal

747

566

View full text Add to dashboard Cite

“…For changes from baseline (baseline score subtracted from month 18), a negative difference suggests a worsening of CRQ, whereas a positive difference suggests an improvement in CRQ. The CRQ is responsive to change among patients with COPD, and the minimal clinically significant difference for each CRQ domain is 0.5 (23,25).…”

Section: Original Research Co-primary Outcomesmentioning

confidence: 99%

A Lifestyle Physical Activity Intervention for Patients with Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial

et al. 2016

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Rationale: Physical inactivity is associated with poor outcomes among patients with chronic obstructive pulmonary disease (COPD).Objectives: To determine effectiveness of a behavioral intervention intended to increase daily physical activity with the goal of improving health-related quality of life and functional performance. Methods:We conducted a randomized trial among patients with COPD cared for in primary care and pulmonary clinics. The patients were at least 45 years of age and eligible for pulmonary rehabilitation. All patients received self-management education during a 6-week run-in period. Subsequently, patients were randomized to usual care or the intervention delivered over 20 weeks.Measurements and Main Results: Co-primary outcomes were change from baseline in Chronic Respiratory Questionnaire dyspnea domain score and 6-minute-walk distance measured at 6, 12, and 18 months after randomization. A total of 325 patients were enrolled, with 156 randomized to receive usual care and 149 to receive the intervention. At 18 months, there was no overall statistical or clinically significant change in the dyspnea domain in either group. However, for 6-minute-walk distance, there were statistically significant declines in both groups. In contrast, 6-minute-walk distance remained stable (5.3 m; P = 0.54) among patients in the intervention group with moderate spirometric impairment, but it was associated with clinically and statistically significant declines (228.7 m; P = 0.0001) among usual care patients with moderate spirometric impairment. Overall, there was no increase in adverse events associated with the intervention, which was associated with a lower prevalence of hospitalization for COPD exacerbations (28.3%) compared with usual care (49.5%).

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“…In the original CRQ, patients choose five important daily activities (individualised dyspnoea items) and report their degree of dyspnoea whilst doing those activities. Individualisation potentially enhances validity and responsiveness (the ability of the CRQ to detect important changes, even if those changes are small) [18].…”

mentioning

confidence: 99%

“…Similarly, while the original CRQ has proved both responsive and valid [21], little is known about the extent to which the individualised questions improve or impair measurement properties. In one observational study and one randomised study performed in German-speaking countries, standardisation of dyspnoea items reduced the time needed for completion of the CRQ from 16 to 8 min, but impaired CRQ responsiveness [18,22]. However, previous studies were limited by small sample sizes and observational designs [18][19][20], and the lack of concomitant administration of other disease-specific instruments needed to test the validity of a standardised CRQ-SA [22].…”

mentioning

confidence: 99%

A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire

Schünemann

Goldstein

Mador³

et al. 2005

European Respiratory Journal

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The original chronic respiratory questionnaire (CRQ), one of the most widely used measures of health-related quality of life (HRQL) in chronic respiratory disease (CRD), is traditionally interviewer administered (IA) and includes an individualised dyspnoea domain. The present authors studied the impact of self-administered (SA) and standardised dyspnoea questions on CRQ measurement properties.In a factorial design multicentre trial, 177 patients with CRD (mean age 67.7 yrs; mean forced expiratory volume in one second per cent predicted 44.6%) were randomised to CRQ-IA (n586) or CRQ-SA (n591), and to initially complete the standardised or individualised items before and after respiratory rehabilitation.While maintaining validity, the CRQ-SA proved more responsive to changes in HRQL than the CRQ-IA in all domains. Compared with the standardised dyspnoea domain, the individualised dyspnoea domain indicated greater responsiveness. The correlations of baseline scores and change scores with other HRQL instruments indicated good validity of the CRQ-SA.In conclusion, self-administration and standardisation of the chronic respiratory questionnaire maintains validity and responsiveness relative to the interviewer-administered chronic respiratory questionnaire. These results challenge the assumption that interviewer-administered questionnaires are superior to self-administered questionnaires in older patients with chronic respiratory disease.

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A Comparison of the Original Chronic Respiratory Questionnaire With a Standardized Version

Cited by 88 publications

References 21 publications

Outcomes for COPD pharmacological trials: from lung function to biomarkers

Outcomes for COPD pharmacological trials: from lung function to biomarkers

A Lifestyle Physical Activity Intervention for Patients with Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial

A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire

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