A comparison of Progrip® and Adhesix® self-adhering hernia meshes in an onlay model in the rat

Gruber-Blum, Simone; Riepl, Nicole; Brand, Jürgen; Keibl, Claudia; Redl, Heinz; Fortelny, René H.; Petter-Puchner, Alexander H.

doi:10.1007/s10029-014-1258-0

Cited by 24 publications

(19 citation statements)

References 26 publications

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“…compared the self-fixation meshes PP and Adhesix TM in an animal study, and showed better results and greater stability for the PP implant, due to the longer effect of adherence provided by its minigrips, which degraded for several months. [ 36 59 ] We could not validate this finding because of lack of experience with this type of mesh.…”

Section: Discussionmentioning

confidence: 98%

Usage of a self-adhesive mesh in TAPP hernia repair: A prospective study based on Herniamed Register

Klobusicky

Feyerherd

2016

J Min Access Surg

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INTRODUCTION:Inguinal hernia repair is one of the most frequently performed surgical procedures worldwide in general surgery. The transabdominal laparoscopic (TAPP) approach in the therapy of inguinal hernia seems to be a suitable alternative to classical open inguinal hernia repair mainly in the hands of an experienced surgeon. TAPP repair offers the possibility of gentle dissection with implantation of the mesh and the possibility of non-invasive fixation of the implanted mesh.MATERIALS AND METHODS:Data analysis encompassed all patients who underwent inguinal hernia surgery at our Surgical Department within the period from July 1, 2012 to September 30, 2014 and who fulfilled the inclusion criteria. The standard surgical technique was used. Data were entered and subsequently analysed on the Herniamed platform. Herniamed is an Internet-based register in German and English, and includes all data of outpatient and hospitalised patients who underwent surgery for some type of hernia. All relevant patient data are collected via Internet.RESULTS:There were 241 patients enrolled in the group and there were 396 inguinal hernias repaired in total. Standard long-term follow-up after 12 months was evaluated in 205 patients (85.06%), and in the rest of the patients during the closing of the study, but at least 6 months after operation. The mean follow-up was at 19.69 months. At the 1-year assessment, mild discomfort was reported in the groin in 10 patients (4.88%) [1-3 on the visual analogue scale (VAS)]. Post-operative pain lasting over 12 months in the groin of moderate degree (4-6 VAS) was reported in two cases (0.97%). There was no recurrence and no chronic post-operative pain of severe degree reported.CONCLUSION:Our study demonstrates that laparoscopic inguinal hernia repair using the TAPP technique with the implantation of a self-fixation mesh is fast, effective, reliable and economically advantageous method in experienced hands and, according to our results, reduces the occurrence of post-herniorrhaphy inguinal pain (CPIP) and has a low recurrence rate.

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Section: Discussionmentioning

confidence: 98%

Usage of a self-adhesive mesh in TAPP hernia repair: A prospective study based on Herniamed Register

Klobusicky

Feyerherd

2016

J Min Access Surg

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“…Self-adhering mesh has been shown to have superior gripping strength to both laparoscopic staples and fibrin glue over the short and medium terms. 11 It has also been shown to incorporate well over the long term, 10 thus acting as a durable reinforcement to the fascia.…”

Section: Discussionmentioning

confidence: 99%

“…The microgrips provide secure mesh fixation and distribute the tension along the entire surface area of the mesh, allowing strong purchase of the mesh against the tissue. 10 The strength of the mesh purchase against tissues has been found to be superior to laparoscopic staples and fibrin glue at 5 days and 2 months, respectively. 11 The mesh also has been found to achieve good tissue incorporation.…”

mentioning

confidence: 99%

Abdominal Wall Reconstruction Using Retrorectus Self-adhering Mesh: A Novel Approach

Khansa

Janis

2016

Plastic and Reconstructive Surgery - Global Open

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“…Its numerous advantages gave a boost to a broad utilization in hernia surgery, including atraumatic fixation and the facility to handle and to orient the mesh under laparoscopic condition. In a rat model investigation, Gruber‐Blum et al demonstrated that this self‐adhesive mesh was perfectly integrated in abdominal muscles, without any signs of implant dislocation and seroma formation (Figure B,C) …”

Section: Enhancement Of Mesh Fixation By Atraumatic Adhesive Systemsmentioning

confidence: 99%

“…However, long‐term clinical studies revealed that this technology was not completely free of side‐effects, and first cases of chronic pain, recurrence and other mesh‐related symptoms have been reported . A competitor company (Cousin Biotech) has launched an auto‐adhesive mesh (Adhesix) based on a monofilament PP implant coated with PEG and PVP, but the few contradictory studies available did not encourage its utilization …”

Section: Enhancement Of Mesh Fixation By Atraumatic Adhesive Systemsmentioning

confidence: 99%

Emerging Trends in Abdominal Wall Reinforcement: Bringing Bio‐Functionality to Meshes

Guillaume

Teuschl

Gruber-Blum

et al. 2015

Adv Healthcare Materials

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Abdominal wall hernia is a recurrent issue world-wide and requires the implantation of over 1 million meshes per year. Because permanent meshes such as polypropylene and polyester are not free of complications after implantation, many mesh modifications and new functionalities have been investigated over the last decade. Indeed, mesh optimization is the focus of intense development and the biomaterials utilized are now envisioned as being bioactive substrates that trigger various physiological processes in order to prevent complications and to promote tissue integration. In this context, it is of paramount interest to review the most relevant bio-functionalities being brought to new meshes and to open new avenues for the innovative development of the next generation of meshes with enhanced properties for functional abdominal wall hernia repair.

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A comparison of Progrip® and Adhesix® self-adhering hernia meshes in an onlay model in the rat

Abstract: In our hands, PP (mechanical grip fixation) was superior to hydrogel fixation with PEG and PVP in AH in an onlay model. The reason for dislocation of AH requires further clarification as well as the impact of long-term degradation of the PLA grips.

Cited by 24 publications

References 26 publications

Usage of a self-adhesive mesh in TAPP hernia repair: A prospective study based on Herniamed Register

Usage of a self-adhesive mesh in TAPP hernia repair: A prospective study based on Herniamed Register

Abdominal Wall Reconstruction Using Retrorectus Self-adhering Mesh: A Novel Approach

Emerging Trends in Abdominal Wall Reinforcement: Bringing Bio‐Functionality to Meshes

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