A comparison of epidural buprenorphine with epidural morphine for postoperative analgesia following stifle surgery in dogs

Smith, Lesley; Yu, Jeff

doi:10.1046/j.1467-2987.2000.00038.x

Cited by 30 publications

(28 citation statements)

References 27 publications

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“…Buprenorphine is a promising drug for epidural analgesia (82) with similar analgesic effect and duration of action when compared to morphine in dogs undergoing stifle surgery (83). Epidural buprenorphine may be useful for some animals because it does not appear to induce the urinary retention due to detrusor muscle relaxation seen with epidural morphine (84).…”

Section: Opioidsmentioning

confidence: 99%

“…Epidural buprenorphine may be useful for some animals because it does not appear to induce the urinary retention due to detrusor muscle relaxation seen with epidural morphine (84). It is apparent that in dogs and humans (83, 85), epidural buprenorphine may induce long lasting analgesia of similar duration of that provided by epidural morphine, but with fewer side effects. However, additional studies are necessary to confirm if the epidural administration of this opioid can replace epidural morphine in dogs.…”

Section: Opioidsmentioning

confidence: 99%

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An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

Steagall

2017

Front. Vet. Sci.

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This review aims to report an update on drugs administered into the epidural space for anesthesia and analgesia in dogs, describing their potential advantages and disadvantages in the clinical setting. Databases searched include Pubmed, Google scholar, and CAB abstracts. Benefits of administering local anesthetics, opioids, and alpha2 agonists into the epidural space include the use of lower doses of general anesthetics (anesthetic “sparing” effect), perioperative analgesia, and reduced side effects associated with systemic administration of drugs. However, the potential for cardiorespiratory compromise, neurotoxicity, and other adverse effects should be considered when using the epidural route of administration. When these variables are considered, the epidural technique is useful as a complementary method of anesthesia for preventive and postoperative analgesia and/or as part of a balanced anesthesia technique.

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Section: Opioidsmentioning

confidence: 99%

Section: Opioidsmentioning

confidence: 99%

An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

Steagall

2017

Front. Vet. Sci.

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“…According to Vettorato et al 10 for dog 1,23,24 . The pain scoring system employed in the current study has been previously described for pain quantification in dogs 17,18,23 .…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have shown satisfactory results following extradural (ED) opioid administration for postoperative pain relief [1][2][3] .…”

Section: Introductionmentioning

confidence: 99%

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A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

et al. 2012

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PURPOSE: To compare the postoperative analgesic effects of the extradural tramadol or morphine in female dogs undergoing ovariohysterectomy. METHODS: Sixteen female dogs were randomly assigned to two groups of eight animals each and received morphine (0.1mg kg-1 M group) or tramadol (2mg kg-1 T group). The pre-anesthetic medication was intravenously (iv) acepromazine (0.05mg kg-1). Anesthesia was induced with propofol (4mg kg-1iv) and maintained with isoflurane. The degree of analgesia was evaluated using a numerical rating scale that included physiologic and behavior variables. Dogs were scored at one, three, six and 12 hours after surgery by one blinded observer. Dogs were treated with morphine (0.5mg kg-1) if their scores were >6. Serum cortisol was measured before the pre-anesthetic medication was administered (basal), at the time of the ovarian pedicle clamping (T0), and at 1 (T1), 6 (T6) and 12 (T12) hours postoperative. RESULTS: The pain score did not differ between morphine and tramadol treatments. Rescue analgesia was administered to one dog in the T treatment group. Serum cortisol did not differ between treatments. CONCLUSION: The extradural administration of morphine or tramadol is a safe and effective method of inducing analgesia in female dogs undergoing ovariohyterectomy.

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Epidural and Spinal Anesthesia

Otero¹,

Campoy²

2013

Small Animal Regional Anesthesia and Analgesia

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A comparison of epidural buprenorphine with epidural morphine for postoperative analgesia following stifle surgery in dogs

Cited by 30 publications

References 27 publications

An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

Epidural and Spinal Anesthesia

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