“…10,11,14,15 Capsular contracture is typically apparent within the first year after implantation, 7,9,14,15 and is likely to mature with time, with accumulating risks over the lifetime of the implant, 16 -18 but the exact etiology and frequency based on modern devices is unknown. Numerous studies have examined the influence of implant filler material, surface texture, silicone bleed, and implant placement on capsular contracture, 13,[15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34] but the findings are contradictory, which may be explained in part by different study designs, indications for surgery, implant types, and length of follow-up, as well as by variations in outcomes of interest (capsular contracture Baker II-IV vs III-IV) and whether analyses were done at breast level or woman level. In a study of symptom reporting by women with cosmetic implants, saline implant, subglandular placement, smooth surface, and postoperative hematoma were associated with increased risk of capsular contracture.…”