A comparison between high hydrostatic pressure extraction and heat extraction of ginsenosides from ginseng (<i>Panax ginseng</i>
 CA Meyer)

Lee, Hyun Sun; Lee, Hyun Jung; Yu, Hyung Jo; Ju, Do Weon; Kim, Yoon‐Sook; Kim, Chong Tai; Kim, Chul Jin; Cho, Yong Jin; Kim, Namsoo; Choi, Sang Yoon; Suh, Hyung Joo

doi:10.1002/jsfa.4334

Cited by 69 publications

(45 citation statements)

References 30 publications

(29 reference statements)

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“…Specifically, the amounts of ginsenosides Rb 2 and Rd in the HRG were highest among the ginseng extracts. Lee et al (8) compared ginsenosides compositions between red ginseng under high hydrostatic pressure extraction (HHPE) and red ginseng under heat extraction (HE). Total ginsenoside and ginsenosides Rg 1 , Rg 2 +Rh 1 , Rb 1 , Rb 2 , Rd, and F2 were increased under HHPE compared to HE.…”

Section: Discussionmentioning

confidence: 99%

“…Usage of low temperature (between −20 and 60 o C) in the HHP process results in an increase of extraction efficiency without destroying heat-sensitive bioactive constituents (7). Lee et al (8) reported that the amount of major ginsenosides found in high hydrostatic pressure extracts of Korea ginseng was 45% more compared to the extracts using conventional methods.…”

Section: Introductionmentioning

confidence: 99%

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High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

Jung¹,

Lee²,

Shin³

et al. 2015

JFN

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Chronic low-grade inflammation is associated with obesity. This study investigated effect of high hydrostatic pressure extract of red ginseng (HRG) on inflammation in rats with high-fat (HF) diet induced obesity. Male, SpragueDawley rats (80∼110 g) were randomly divided into two groups, and fed a 45% HF diet (HF) and a 45% HF diet containing 1.5% HRG (HF+HRG) for 14 weeks. At the end of the experiment, the serum leptin level was reduced by the HRG supplementation. The mRNA expression of genes related to adipogenesis including peroxisome proliferator-activated receptor-gamma and adipocyte protein 2 was down-regulated in the white adipose tissue (WAT). The mRNA levels of major inflammatory cytokines such as tumor necrosis factor-, monocyte chemoattractant protein 1, and interleukin-6 were remarkably down-regulated by the HRG in WAT. These results suggest that HRG might be beneficial in ameliorating the inflammation-associated health complications by suppressing adipogenic and pro-inflammatory gene expression.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

Jung¹,

Lee²,

Shin³

et al. 2015

JFN

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“…The reason for higher extraction of Rg1 and Rb1 in the three-enzyme combination CAP could be due to the enhanced activity of cellulase and amylase at HHP as reported earlier. Additionally, HHP was reported to disrupt ginseng cells and release the starch materials;[3233] hence treatment with cellulase and amylase hydrolyze the cellulose in the cell wall and starch released from the cells, respectively, to facilitate higher release of ginsenosides. We observed, in our previous study, that treatment with cellulase converts ginsenoside Rb1 to Rd.…”

Section: Discussionmentioning

confidence: 99%

Preparation of ginseng extract with enhanced levels of ginsenosides Rg1 and Rb1 using high hydrostatic pressure and polysaccharide hydrolases

Palaniyandi¹,

Suh²,

Yang³

2017

Phcog Mag

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Background:Ginsenosides are the principal components responsible for the pharmacological activities of ginseng. Ginsenosides Rg1 and Rb1 are the major compounds recognized as marker substances for quality control of ginseng-based products. These major compounds can be transformed to several pharmacologically active minor ginsenosides by chemical, microbial, and enzymatic means.Materials and Methods:In the present study, a combination of polysaccharide hydrolases and high hydrostatic pressure (HHP) were used to extract ginseng saponins enriched with ginsenosides Rg1 and Rb1. Temperature, pH, time, ginseng-to-water ratio, and pressure were optimized to obtain the maximum amount of Rg1 and Rb1 in the resulting extract using commercial polysaccharide hydrolases.Results:This study showed that treatment with a combination of cellulase, amylase, and pectinase at 100 MPa pressure, pH 4.8, and 45°C for 12 h resulted in higher Rg1 and Rb1 levels in the extract.Conclusion:This study describes a cheap and ecofriendly method for preparing ginseng extract enriched with Rg1 and Rb1.SUMMARY Ginsenosides are the principal bioactive components present in ginsengGinsenosides Rg1 and Rb1 are the most abundant compounds in ginsengHigh hydrostatic pressure (HHP) and Polysaccharide hydrolases (PH) were combined to extract ginseng saponins enriched with Rg1 and Rb1Extraction conditions were optimized to obtain the maximum amount of Rg1 and Rb1Extraction with a combination of cellulase, amylase, and pectinase at 100 MPa pressure at pH 4.8, and 45°C for 12 h resulted in higher levels of Rg1 and Rb1 in the ginseng extract Abbreviations used: ATCC: American Type Culture Collection, Mpa: Mega Pascal

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“…The technique not only took a shorter time but also afforded higher extraction yields of ginsenosides (Yutang et al 2008 ). High-pressure extraction of fresh and red ginseng was found to be more effective than thermal extraction (Lee et al 2011 ).…”

Section: Herbs and Rootsmentioning

confidence: 99%

Recent Developments in High Pressure Processing of Foods

Rastogi¹

2013

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A comparison between high hydrostatic pressure extraction and heat extraction of ginsenosides from ginseng (Panax ginseng CA Meyer)

Abstract: HHPE used for red ginseng processing contributes to enhanced extraction efficiencies of functional materials such as ginsenosides through cell structure modification.

Cited by 69 publications

References 30 publications

High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

Preparation of ginseng extract with enhanced levels of ginsenosides Rg1 and Rb1 using high hydrostatic pressure and polysaccharide hydrolases

Recent Developments in High Pressure Processing of Foods

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