A comparative study of the toxic effect of ZIF-8 and ZIF-L on the colonization and decomposition of shaded outdoor mice carrions by arthropods

Abstract

Metal–organic frameworks (MOFs) are promising materials for several applications. Thus, they have been intensively reported and commercialized by several international companies. However, little is known about the fate and risk of MOFs to living organisms. Here, the toxic effect of two Zinc (Zn)-based MOFs; zeolitic imidazolate frameworks (ZIF-8) and leaf-like ZIF (ZIF-L), was tested to investigate the impact of the postmortem period of mice carrions and arthropods which found in decomposing carrions. The data analysis revealed an increase in zinc content over time. Toxicology in forensics studies biological materials for the presence of poisons, such as pharmaceuticals. The toxicology report can provide important details about the types of chemicals present in a person and whether the amount of those substances is in line with a therapeutic dose or exceeds a dangerous level. These findings conclude the possible fate and impact after mortality. This study presents the first study of the toxic effect of ZIFs materials using mice carrions and arthropods (Sarcophaga sp. Larvae) via morphological and microscopic studies compared with control, providing important biological information could aid in the environmental impact of the toxic level of MOF materials.

Electrospray-on-Electrospun Breathable, Biodegradable, and Robust Nanofibrous Membranes with Photocatalytic Bactericidal Activity

“…ZIF-8 demonstrated its high activity in photocatalytic reactions like CO 2 reduction, E. coli inactivation as well as antibacterial capability with high structure stability. ,, The toxicity of ZIF-8 is very low and has been used for bioapplications. , Thus, ZIF-8 NPs were selected as the functional heterophases for air filtration/purification and antibacterial applications. For a smooth ZIF-8 electrospray, the ZIF-8 NPs are required to be predispersed in the solvent, which is also compatible with the HFP solvent that dissolves PLA/PHBR.…”

“…42,62,63 The toxicity of ZIF-8 is very low and has been used for bioapplications. 64,65 Thus, ZIF-8 NPs were selected as the functional heterophases for air filtration/purification and antibacterial applications. For a smooth ZIF-8 electrospray, the ZIF-8 NPs are required to be predispersed in the solvent, which is also compatible with the HFP solvent that dissolves PLA/PHBR.…”

Advanced Multifunctional Materials (2023)

“…Thus, ZIF-8 was widely used for biomedical applications [192] including gene delivery [193]. However, our recent study showed the transfer of the metal ions into the environment that caused a significant effect on the colonization and decomposition of shaded outdoor mice carrions by arthropods [194].…”

3D printing of cellulose/leaf-like zeolitic imidazolate frameworks (CelloZIF-L) for adsorption of carbon dioxide (CO2) and heavy metal ions

“…ZIF-L was prepared via a one-pot method. 53,54 Typically, Zn (NO 3 ) 2 •6H 2 O (5 mmol, 1.5 g) was dispersed in TOCNF (100 mL, 1.5 wt.%) using an Ultra Turrax (IKA) at 15 000 rpm for one hour. NaOH (10 mL, one mmol) was then added dropwise with stirring.…”