A Comparative Study of Maternal and Fetal Outcome in Obese Non- Obese Pregnant Women

Abstract

Objective: The aim of this study is to determine the adverse pregnancy outcomes in obese and non- obese women. Study Design: Randomized controlled trial Place and Duration: Department of Gyne & Obs, Shahida Islam Teaching Hospital Lodhran, during from 01-07-2020 to 31-07-2021. Methods: Total one hundred and eighty patients were enrolled in this study. Patients were aged between 18- 50 years. Patients detailed demographics were recorded after taking written consent. Patients were equally divided into two groups I and II. 90 obese patients were included in group I and equally non-obese patients were included in group II. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were also calculated among both groups. Fetal outcomes were perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. Complete data was analyzed by SPSS 24.0 version. Results: Mean age of the patients in group I was 34.12±4.59 years with mean BMI 31.12±8.67 Kg/m2 and in group II mean age was 26.13 ±5.78 years with mean BMI 23.03±9.48 Kg/m2. Frequency of pre-eclampsia in obese group I were high among 40 (44.4%) patients as compared to group II 9 (10%) patients , frequency of gestational diabetes mellitus in group I was among 21 (23.3%) patients and 6 (6.7%) patients were in group II, post partum haemorrhage was seen in 57 (63.3%) cases in group I and 29 (32.2%) cases in group II. Fetal outcomes, perinatal mortality in group I 5 (5.5%) and in group II was 4 (4.4%), low birth weight in group I was among 21 (23.3%) and in group II was 45(50%), low apgar score in group I was 14 (15.5%) and in group II was 9 (10%), 43 (47.8%) in group I went to NICU admission and 28 (31.1%) patient in group II admitted to NICU. Conclusion: Pregnancy-related complications such as gestational diabetes, pre-term labour, and pre-eclampsia are more likely in obese women, according to our data. Having a baby with a woman who is obese might lead to serious difficulties for both mother and baby. Maternal obesity is connected with an increased risk of feto-maternal morbidity and mortality. Keywords: Pre-eclampsia, Gestational diabetes, Partum haemorrhage, Apgar score, NICU

The Relationship Between Maternal Obesity with Pregnancy-Associated Hypothyroidism, Fetal Health, and Pregnancy Outcomes

“…Similarly, preeclampsia hypertension, preeclamptic toxemia (PET), and eclampsia were 3.5 times, 2.8 times, and 4.5 times higher for overweight pregnant women than non-overweight pregnant women in India [14,25]. In Pakistan, PET, in obese pregnant women was more than 15% higher compared to normal-weight pregnant women, eclampsia was three-fold greater in obese women, and gestational diabetes mellitus was higher at 23.3% as compared to 6.7% in non-obese [26].…”

“…Older age pregnant women are more likely to develop thyroid dysfunction, pregnancy complications, and congenital or neurocognitive fetal complications [15,26,27]. However, other studies have suggested that obesity, primiparity, and younger age had abnormal levels of FT4 at all trimesters, higher TSH, pregnancy complications, and offspring problems [27,28].…”