A comparative study for the efficacy of different forms of ozone as a treatment for alveolar osteitis

Abstract

Purpose Dry socket is one of the most common complications following dental extraction. Although blood clot disintegration is known to be the cause of the condition, an agreement is lacking regarding the relative merits of various treatment methods. Despite the fact that ozone is one recommended therapy, the literature is deprived of any comparative study for the different forms of ozone delivery. The aim of the current study therefore was to evaluate the efficacy of different forms of ozone as a treatment for this condition. Methods A total of 1521 patients were categorized into four groups (I, II, III and IV) according to pain severity depending on the need and the response to analgesics (mild, moderate, severe or agonizing, respectively). Each group was randomly and blindly divided into three subgroups according treatment method: Oleozon (Ole) which is an ozonized olive oil, ozonized water (OW), ozone gas (O3). Results While Ole, OW and O3 were curative in groups I and II, only O3 was curative for groups III and IV. OW was palliative in group IV. Only O3 was definitive therapy for all groups. Conclusion Ozone in the gaseous form is the most potent form of ozone therapy. Although ozonized oil shows the weakest form, OW had an intermediate potency.

Oleozon Versus Major Autohemotherapy in the Treatment of Dry Socket

“…The results of the current study agree with those of other researches [14][15][16] . However, further studies are needed.…”

“…Dry socket is a very common complication follows dental extraction [1] with pain is the most important clinical issue but with a great controversy about the efficacy of its treatment methods [2][3][4][5] . Of these treatment modalities, ozone was utilized in a limited number of researches with promising results [9,13,14] due to capability to deliver oxygen to the ischemic tissues, and therefore, improves the metabolism and the healing and activates the immune system [7][8][9][10][11] . However, researches to compare the efficacy of different forms of ozone to treat DS is not enough [17] .…”

“…Since Wolff has introduced ozone major autohemotherapy (AHT), it was used as a treatment method for a variety of conditions [12] including DS [13] . Oleozon is an ozonized olive oil used to treat the dry socket [9,14,15] . No enough…”