A Comparative Evaluation of Liver Lobe Size/Albumin Ratio and Platelet Count/Spleen Diameter Ratio as Non-Invasive Predictors of Oesophageal Varices in Patients With Liver Cirrhosis

Charan, Shiv; Garg, Robin; Chander, Rakesh; Singh, Gurminder; Garg, Sudhanshu; Akanksha, Akanksha; Tandon, Rupinder; Joshi, N. J.

doi:10.14260/jemds/2017/409

Cited by 3 publications

(9 citation statements)

References 34 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sensitivity, specificity, positive and negative predictive value (PPV & NPV), and accuracy of the RLLD/Alb ratio were found to be 85.3%, 68.8%, 85.3%, 68.8% and 80.0%, respectively, at the best cut-off value of 4.01. Several other studies13,18,19,21,23 also investigated the potentiality of the RLLD/ Alb ratio for noninvasively predicting the EV and explored a similar positive correlation, implying it as a promising noninvasive tool.…”

mentioning

confidence: 80%

“…Identification and grading of EV were carried out by UGIT endoscopy. 13 Child‐Pugh classification was also utilized to classify patients as A, B, and C grades. Data were accumulated employing a predetermined questionnaire.…”

Section: Methodsmentioning

confidence: 99%

“…Right liver lobe size in diameter (cm) was determined through the abdominal ultrasonography at the mid‐clavicular line by a consultant sonologist. Identification and grading of EV were carried out by UGIT endoscopy 13 . Child‐Pugh classification was also utilized to classify patients as A, B, and C grades.…”

Section: Methodsmentioning

confidence: 99%

“…These methods for the prediction of EV are simple to perform, low cost, and non-invasive due to their requirement of ultrasonography and biochemical tests, which can be regularly executed in patients with liver cirrhosis. 13 Alempijevic T et al showed that RLLD/Alb ratio as a noninvasive way to predict the EV which can easily obtained by performing an ultrasonography and measuring serum albumin concentration. 14,15 Afterward, several studies have been carried out to validate this ratio as a diagnostic tool which found to be same.…”

Section: Introductionmentioning

confidence: 99%

“…These methods for the prediction of EV are simple to perform, low cost, and non‐invasive due to their requirement of ultrasonography and biochemical tests, which can be regularly executed in patients with liver cirrhosis. 13 …”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients

Chowdhury

Palit

Mozibullah

et al. 2022

Clinical Laboratory Analysis

View full text Add to dashboard Cite

Background Endoscopy has long been widely used to screen for esophageal varices (EV) in cirrhotic patients. Recurrent endoscopy is a significant burden for the healthcare system of the endoscopic unit as well as uncomfortable and high costs for patients. This study intended to prognosticate Right Liver Lobe Diameter/Serum Albumin Ratio (RLLD/Alb) as a non‐invasive approach in the early diagnosis of EV among chronic liver disease (CLD) Bangladeshi patients enrolled in a specific hospital. Participants and Methods A total of 150 admitted patients with CLD were included in the study. Patients were subjected through a comprehensive biochemical checkup and upper digestive endoscopic or ultrasonographic inspection. The correlation was evaluated between the RLLD/Alb ratio and esophageal varices grades. Results The upper digestive endoscopy demonstration among 150 patients resulted in no EV in 18%, while 24% of patients was identified as EV grade I, 20% as grade II, 20% as grade III, and 18% patients as grade IV. The mean value of the RLLD/Alb ratio was 4.89 ± 1.49 (range from 2.30 to 8.45). The RLLD/Alb ratio diagnosed the EV employing the cut‐off value of 4.01 with 85.3% sensitivity and 68.8% specificity. Furthermore, it was positively correlated with the grading of EV, when this ratio increased the grading of EV increases and vice versa (r = 0.630, p < 0.001). Conclusion The RLLD/Alb ratio is a non‐invasive parameter giving exact guidance relevant to the ascertainment of the existence of EV and their grading in chronic liver disease patients.

show abstract

mentioning

confidence: 80%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients

Chowdhury

Palit

Mozibullah

et al. 2022

Clinical Laboratory Analysis

View full text Add to dashboard Cite

show abstract

Assessment of Right Liver Lobe Size / Serum Albumin Ratio as a New Non-Invasive Predictor for the Presence of Oesophageal Varices in Egyptian Patients with HCV Related Liver Cirrhosis

Awad

Yousry

Hasan

et al. 2020

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

Assessment of Right Liver Lobe Size/Serum Albumin Ratio as A New Non-Invasive Predictor for The Presence of Oesophageal Varices in Egyptian Patients with HCV Related Liver Cirrhosis

2023

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

Background: Oesophageal varices (OV) are discovered in 24% and up to 80% of cirrhotic liver cirrhotic patient and the severity of varices differs from patient to another, oesophageal endoscopy is the best method for evaluating OV. Objective: As a non-invasive indicator of OV in cirrhotic patients, we hypothesize that we can use the right liver lobe diameter/serum albumin ratio. This will allow us to limit the usage of screening endoscopy. Patients and Methods: Sixty individuals with cirrhotic liver were included in this cross-sectional analysis. Two equal groups of patients (N=30) were formed: Group (1), which included patients with cirrhosis due to HCV infection with or without LCF and Group (2), which included patients with matching ages and sexes who were visiting an endoscopic unit for problems other than cirrhosis. Results: Oesophageal varices was statistically correlated with Rt liver lobe diameter/serum albumin ratio (RLLD/Alb). The sensitivity and specificity were 95.7 % and 93.3% respectively and the cutoff point value was >3.98. Plt count/spleen diameter ratio (P/S) demonstrated a statistical correlation with incidence of esophageal varices. The sensitivity was 90.4% and specificity was 98.2% with best cutoff point value≤16.3. Conclusions: Physicians can benefit from using RLLD/Alb (with or without P/S) as a non-invasive OV predictor.

show abstract

A Comparative Evaluation of Liver Lobe Size/Albumin Ratio and Platelet Count/Spleen Diameter Ratio as Non-Invasive Predictors of Oesophageal Varices in Patients With Liver Cirrhosis

Cited by 3 publications

References 34 publications

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients

Assessment of Right Liver Lobe Size / Serum Albumin Ratio as a New Non-Invasive Predictor for the Presence of Oesophageal Varices in Egyptian Patients with HCV Related Liver Cirrhosis

Assessment of Right Liver Lobe Size/Serum Albumin Ratio as A New Non-Invasive Predictor for The Presence of Oesophageal Varices in Egyptian Patients with HCV Related Liver Cirrhosis

Contact Info

Product

Resources

About