A combined physicochemical and computational investigation of the inclusion behaviour of 3-(1-Naphthyl)-D-alanine Hydrochloride insights into β-Cyclodextrin

Exploring Brilliant Blue FCF Assembly with Beta Cyclodextrin, Characterizations and Applications in Biological Systems Using Physicochemical and Computational Methods

“…CDs have a hydrophilic outer surface, internal hydrophobic cavity, and various interactions like dipolar, hydrogen bonding, and Van der Waals forces arising between the host moiety and guest molecule making CDs act as the perfect 'host' for incorporating individual compounds like drugs, and amino acids, dyes, ionic liquids, etc. [9] Aromatic organic compounds are suitable guests as they have excellent docking abilities of the apolar aromatic ring, by creating hydrophobic interactions with the cavity of the host β-CD molecule. [10] As the CDs have good binding properties, they can form stable inclusion complexes (ICs) with various bioactive and industrially essential compounds i. e., drugs, food additives, etc which are promising for biological and computational applications.…”

“…β‐CD has a hydrophobic inner cavity and hydrophilic outer surfaces. CDs have a hydrophilic outer surface, internal hydrophobic cavity, and various interactions like dipolar, hydrogen bonding, and Van der Waals forces arising between the host moiety and guest molecule making CDs act as the perfect ‘host’ for incorporating individual compounds like drugs, and amino acids, dyes, ionic liquids, etc [9] . Aromatic organic compounds are suitable guests as they have excellent docking abilities of the apolar aromatic ring, by creating hydrophobic interactions with the cavity of the host β‐CD molecule [10] .…”