1950
DOI: 10.1210/jcem-10-1-54
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A Color Test for Dehydroisoandrosterone and Closely Related Steroids, of Use in the Diagnosis of Adrenocortical Tumors

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Cited by 114 publications
(15 citation statements)
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“…Authentic steroid markers were run alongside and were detected by UV light (254 nm wavelength) for 4-en-3-oxosteroids or with iodine vapour and Allen reagent (Allen, Hayward & Pinto, 1950). This method success¬ fully resolved 5oc-androst-16-en-3-one, 5oc-androst-16-en-3a-ol and 4,16-androstadien-3-one from each other and from a mixture of 5a-androst-16-en-3ß-ol plus 5,16-androstadien-3ß-ol.…”
Section: Separation Of Metabolitesmentioning
confidence: 99%
“…Authentic steroid markers were run alongside and were detected by UV light (254 nm wavelength) for 4-en-3-oxosteroids or with iodine vapour and Allen reagent (Allen, Hayward & Pinto, 1950). This method success¬ fully resolved 5oc-androst-16-en-3-one, 5oc-androst-16-en-3a-ol and 4,16-androstadien-3-one from each other and from a mixture of 5a-androst-16-en-3ß-ol plus 5,16-androstadien-3ß-ol.…”
Section: Separation Of Metabolitesmentioning
confidence: 99%
“…It is of interest that the dehydroisoandrosterone test (7), which is generally considered to be more likely to yield a positive result in adrenal tumors, was of no help in the differential diagnosis in this case. In fact, the negative result was misleading.…”
mentioning
confidence: 92%
“…The technic for total neutral 17-ketosteroids was a modification of that described by HoltorfT and Koch (1). Dehydroisoandrosterone was determined by the method of Allen, Hayward, and Pinto (2). In the 2 patients with increased neutral 17-ketosteroid excretions, the "phenolic fraction" obtained by extraction with IN KOH was separated from the carbon tetrachloride extract and was used for bioassay of estrogens.…”
Section: Introductionmentioning
confidence: 99%