A clubbed quinazolinone and 4-thiazolidinone as potential antimicrobial agents

Desai, N. C.; Dodiya, Amit M.; Shihora, P. N.

doi:10.1007/s00044-011-9674-5

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Anti-microbial Hybrids1

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Cited by 15 publications

(2 citation statements)

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“…Desai et al have synthesized novel 5-arylidine derivatives of thiazolidin-4-one and quinazolin-4(3H)one. 89 No derivative was found to be exceptionally potent in anti-microbial screening. Amongst them, compound 65a was found to be potent, with the MIC value of 25 mg mL À1 against E. coli.…”

Section: Anti-microbial Hybridsmentioning

confidence: 99%

Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids

2020

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Section: Anti-microbial Hybridsmentioning

confidence: 99%

Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids

2020

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“…Reactions on solid support without using solvent usually with closed vessels in a Synthos-3000, Anton Paar MW reaction system is currently popular among synthetic chemists to create an ecofriendly condition. [40] A number of commercially available hydrazides were treated with different carboxylic acids in the presence of phosphorous oxychloride to afford 2,5-disubstituted-1,3,4-oxadiazoles (Scheme 26). To establish the general validity of the newly developed method, several selected one-pot MW-assisted syntheses were carried out.…”

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confidence: 99%

Microwave-Assisted Synthesis of Five-MemberedO,N,N-Heterocycles

Kaur

2014

Synthetic Communications

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The development of new strategies for synthesis of five-membered O,N,Nheterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen and two nitrogen atoms containing five-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5-10 years. This contribution covers the literature concerning the total synthesis of five-membered O,N,N-heterocycles.

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