A clinicopathological study on verrucous hyperplasia and verrucous carcinoma of the oral mucosa

Abstract

Clinicopathological features of VH and VC in China were elucidated. Elderly patient with oral verrucous lesion located on the lower lip correlates with higher risk of carcinoma.

Exophytic oral verrucous hyperplasia: a new entity

“…VC is distinguished histologically from OVH by the presence of an endophytic growth of the hyperplastic epithelium (pushing borders) in the lamina propria, below the level of the adjacent epithelium . Apart from this there have been reports on the presence of dysplasia in verrucous hyperplasia …”

“…They concluded that, the term OVH could be applied clinically and histopathologically only to the “mass type lesions” and that the “plaque type lesions” be clinically termed oral verruciform leukoplakia. In a few clinico‐pathological studies conducted in the Taiwanese population, OVH has been recognized to be a potentially malignant disorder.…”

Localisation orale de condylome acuminé : à propos de 3 cas cliniques et revue de littérature

“…Sa morbidité est assez élevée à cause de son agressivité locale et la fréquence des récidives après traitement [19], [20]. Il intéresse pré-férentiellement la gencive attachée et la muqueuse jugale [19], [21]. Cliniquement, il se présente sous forme d'une prolifération verruqueuse exophytique kératinisée, sans induration classique [15], [19].…”

Oral Potentially Malignant Disorders: An Overview of More than 20 Entities

“…VH is characterized by the thickened epithelium with superficial to adjacent normal epithelium, whereas verrucous carcinoma is characterized by an invaded pushing border of the hyperplastic epithelium to connective tissue, but the basement membrane is intact. In addition, Zhu et al 37 demonstrated that VH located on the lower lip had a higher risk of malignant transformation compared with other sites. Despite the rarity of VH in Western countries, it is a quite common oral premalignant lesion in Taiwan.…”