A clinicopathological study of so-called denture fibroma.

Sasat, Hirofumi; Yamamoto, Hirotsugu; Matsumoto, Takashi; Fukumoto, Masahiko; Otake, Shigeo; Kobayashi, Kihei; Kato, Yoshiaki; Fujii, Akira

doi:10.2334/josnusd1959.32.204

Cited by 4 publications

(12 citation statements)

References 7 publications

(15 reference statements)

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“…Histopathologically, the combination of fibrous and inflammatory granulation was predominant in previous report 10) .…”

Section: Discussionmentioning

confidence: 86%

“…It is relatively a common lesion with an incidence rate of 4.9 to 18.0% among denture wearers. Predilections in the anterior region, among female patients, complete denture wearer, and in those patients where the denture has been worn for more than 10 years have been described in previous epidemiological studies [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] .…”

Section: Introductionmentioning

confidence: 99%

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So-called ^|^ldquo;Denture Fibroma^|^rdquo;: A Histopathological and Immunohistochemical Study

Wakami

Kuyama

Sun

et al. 2012

J. Hard Tissue Biology.

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The purpose of this study was to investigate the histopathological and immunohistochemical characteristics of so-called "denture fibroma" and related stromal reaction. The tissues were histologically classified into inflammatory granulation type, matured fibrous type and myxoid type. Tenascin, LOX, fibrinogen and COX were strongly detected in inflammatory granulation type whereas a weak expression was detected in matured fibrous type. LOX was remarkably expressed by spindle shaped cells/fibroblastic cells and endothelial cells while tenascin was relatively expressed by monocytes in myxoid type. Despite strong expressions of tenascin, fibrinogen, COX-2 and LOX, their expressions decreased towards the deep part of the connective tissue. The greatest number of vessels was obtained in inflammatory granulation type and the least number of vessels was obtained in myxoid type which might contribute to hypoxic condition.The results suggest that the so-called "denture fibroma" is a consequence of acute inflammatory reaction leading to the formation of inflammatory granulation followed by the state of fibrosis which gradually was replaced by matured collagen fibers. Furthermore, myxoid degeneration occurred when blood vessels decreased which lead to hypoxic condition.

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“…Histopathologically, the combination of fibrous and inflammatory granulation was predominant in previous report 10) .…”

Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

So-called ^|^ldquo;Denture Fibroma^|^rdquo;: A Histopathological and Immunohistochemical Study

Wakami

Kuyama

Sun

et al. 2012

J. Hard Tissue Biology.

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“…Several reports mentioned that complete denture wearer suffered more with denture fibroma than partial denture wearer 3,4,16) but Dundar N. and Ilhan Kal B. reported a predominance among partial-denture wearer 2) .…”

Section: Review Of Literaturesmentioning

confidence: 99%

“…An incidence of 4.9 to 18.0% 1-3, 11, 12, 20-23) was reported among denture wearers. Regarding gender, studies mentioned that male 2-4, 10, 12) and female were both affected 6,9,11,16) . Seventy percent of the patients were 40 years old and above 10) .…”

Section: Review Of Literaturesmentioning

confidence: 99%

“…Various terms referring to a hyperplastic tissue associated with ill-fitting denture have been used. Some of the terms used were denture hyperplasia 2-5) , hyperplasia caused by dentures 6) , denture irritation hyperplasia 1, 7) , denture-induced hyperplasia 8) , denture-induced fibrous hyperplasia 9,10) and denture-induced inflammatory fibrous hyperplasia [11][12][13] , epulis fissuratum 9,14,15) , so-called "denture fibroma" 16) and denture injury . However, the term 'Flabby gum: mobile soft membrane tissue with the tactile feeling of "Konjac" at the residual ridges of the maxilla and mandible' was not included in this study.…”

Section: Review Of Literaturesmentioning

confidence: 99%

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So-Called ^|^ldquo;Denture Fibroma^|^rdquo;: A Retrospective Clinico-Pathological Study and Review of Literatures

Wakami

Kuyama

Sun

et al. 2012

J. Hard Tissue Biology.

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Abstract:The purpose of this study was to determine the clinico-pathological characteristics of so-called "denture fibroma" and to perform a review of literature. A comparative analysis was carried out to clarify the epidemiological characteristics of the lesion. A total of 142 cases (average age of 65.2 ± 11.1 years), predominantly female, with so-called "denture fibroma" was examined. The residual alveolar ridge in the posterior region (43.7 %) and in the anterior region (43.0 %) was affected with almost the same tendency. However, significant difference in the frequency between the maxilla and mandible was not observed. Macroscopically, majority of the lesions ranged from 1.1 -2.0 cm (52.5%) and 0.1-1.0 cm 3 (59.0%) in diameter. Histopathologically, myxoid degeneration (55.7%) was the most common feature and the presence of minor salivary gland in the connective tissue (26.2%) was observed simultaneously. In the review of literature, the incidence of denture fibroma ranged from 2.0 to 15.0% of the number of cases investigated. The number of cases among denture wearers ranged from 4.9 to 18.0% as reported. Regarding gender, the lesion affects both male and female with equal predominance. In other patients, the lesion was predominantly observed in elderly people with complete denture. Regarding the site of the lesion, the maxilla was reported to be the favored site. When the anterior and posterior regions were compared, many cases of denture fibroma arose in the anterior region overwhelmingly. A denture worn for more than 10 years was reported to be relevant in the development of so-called "denture fibroma".

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An assessment of mast cells and myofibroblasts in denture‐induced fibrous hyperplasia

Kiuchi

Yamamura

Okudera

et al. 2013

J Oral Pathology Medicine

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A clinicopathological study of so-called denture fibroma.

Cited by 4 publications

References 7 publications

So-called ^|^ldquo;Denture Fibroma^|^rdquo;: A Histopathological and Immunohistochemical Study

So-called ^|^ldquo;Denture Fibroma^|^rdquo;: A Histopathological and Immunohistochemical Study

So-Called ^|^ldquo;Denture Fibroma^|^rdquo;: A Retrospective Clinico-Pathological Study and Review of Literatures

An assessment of mast cells and myofibroblasts in denture‐induced fibrous hyperplasia

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