A clinico-epidemiological study of dermatoses in pediatric HIV patients in a tertiary care center

Nair, Sukumaran Pradeep; Mathew, Rony

doi:10.4103/2319-7250.179487

Cited by 4 publications

(12 citation statements)

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“…3,14,15,[18][19][20][21] Half (55%) of the seropositive patients had migrated, and 18.5% patients had separated from their partners (either divorced or widow) comparing well with the findings of Rodrigues and Bachmann et al 3,20 Most of the seropositive male patients (two-thirds) gave history of contact with CSW and also multiple sexual contacts (more than 6) in the past 6 months. This is because CSWs still serve as source of infection pool for HIV.…”

Section: Demographic Profile Of Patients Presenting To Std Clinicsupporting

confidence: 74%

“…3,12,16,21 The majority (85.2%) of the HIV-seropositive patients were either unemployed or unskilled workers, belonging to lower socioeconomic strata and having multiple addictions, for example, smoking, alcoholism, and tobacco chewing in concordance with studies in the literature. [19][20][21] Although unprotected sexual contact was commoner in the seropositive group, the difference was not significant when compared to seronegative patients. This is because lack of condom use facilitates transmission of both HIV and other STIs.…”

Section: Demographic Profile Of Patients Presenting To Std Clinicsupporting

confidence: 70%

“…16,19 Heterosexual contact was the commonest type of sexual contact (78%) followed by bisexual contact which compares well with the other studies. 3,14,16,19,21 There was no significant difference in the knowledge and awareness regarding HIV infection, as there is in general lack of awareness regarding HIV and protective role of condoms. 3,13,21 Importantly 3 of the 27 seropositive patients had history of intravenous drug abuse, which is increasingly becoming an important risk factor for HIV transmission (risk factor ¼ 0.3) 3,10,18 …”

Section: Demographic Profile Of Patients Presenting To Std Clinicmentioning

confidence: 95%

“…This is because lack of condom use facilitates transmission of both HIV and other STIs. 10,16,21 Sexual mode of transmission was the cause of HIV in 96.3% patients, which is the commonest mode of HIV transmission in developing nations such as India. 16,19 Heterosexual contact was the commonest type of sexual contact (78%) followed by bisexual contact which compares well with the other studies.…”

Section: Demographic Profile Of Patients Presenting To Std Clinicmentioning

confidence: 99%

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Clinico-Epidemiological Profile of Viral Sexually Transmitted Infections in Seropositive Patients Attending a Tertiary Care Hospital in North India

Chugh

Garg

Sarkar

et al. 2017

J Int Assoc Provid AIDS Care

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Sexually transmitted diseases are a major public health problem both in developing and in developed countries, and especially with the co-synergy with HIV infection, there is an increasing need to have a proper understanding of the clinicodemographic patterns of sexually transmitted infections (STIs) for planning and implementing control strategies. Worldwide, there is an increased preponderance of viral STIs. Increasing incidence and altered clinical presentation of viral STIs in patients with HIV pose a diagnostic challenge; thereby, we studied the demographic profile of HIV-seropositive patients and compared clinical manifestations of viral STIs in HIV-seropositive patients to those in seronegative individuals. Twenty-seven HIV-seropositive patients with viral STI (herpes/molluscum/warts) and same number of age-, sex-, and STI-matched seronegative patients were studied for variability in clinical profile. There were significant differences in the demographic factors (education, income, and migration) and sexual practices (number of contacts and source of infection) in the 2 groups. Lesional symptoms, increased extent of lesions, and resistance to treatment were significantly more common in HIV-seropositive patients.

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Section: Demographic Profile Of Patients Presenting To Std Clinicsupporting

confidence: 74%

Section: Demographic Profile Of Patients Presenting To Std Clinicsupporting

confidence: 70%

Section: Demographic Profile Of Patients Presenting To Std Clinicmentioning

confidence: 95%

Section: Demographic Profile Of Patients Presenting To Std Clinicmentioning

confidence: 99%

See 2 more Smart Citations

Clinico-Epidemiological Profile of Viral Sexually Transmitted Infections in Seropositive Patients Attending a Tertiary Care Hospital in North India

Chugh

Garg

Sarkar

et al. 2017

J Int Assoc Provid AIDS Care

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“…15 It was very less compared to study by Sukumaran et al, but the study was carried out on only pediatric population. 16 Biopsy-confirmed cases of eosinophilic pustular folliculitis were detected in 6.2% of patients. The lesions mostly appeared as discrete, erythematous papules on the face and upper arms and they were severely pruritic.…”

Section: Discussionmentioning

confidence: 99%

Dermatological manifestations of acquired immunodeficiency syndrome: an observational study among HAART naive patients from an ART centre of excellence

Sailo¹,

Devi²,

Singh

et al. 2017

Int J Res Dermatol

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Background: Dermatological manifestations can be a window to the clinical and immunological status of patients with HIV infection. Introduction of HAART has dramatically shifted the pattern of HIV associated dermatoses. The present study has been carried out to find out the same among HIV infected patients not started on HAART therapy.Methods: Two hundred (200) HIV-positive, HAART-naïve patients attending ART centre of excellence were examined between November 2005 to July 2007, for the presence of mucocutaneous manifestations, correlation with CD4 count and analyzed using SPSS software.Results: Out of the 200 patients examined, 64.5% (n=129) were found to have mucocutaneous manifestations. Out of those 129 patients 70 (54.3%) were male and 59 (45.7%) were females. Age of the patients ranged from 5 to 62 years with a mean±S.D of 32.08±11.48 yrs. Fungal infections (n=67, 51.9%) were the most common infectious dermatoses, followed by viral infections (n=35, 27.1%), scabies infestations (n=17, 13.2%) and bacterial infections (n=2, 1.6%). Of all the fungal infections, candidiasis (43.28%) was the commonest. Majority (64.5%) of the mucocutaneous manifestations were seen in patients with CD4 count <200 cells/mm3 and difference in CD4 count was significantly associated with cutaneous penicilliosis and oral hairy leukoplakia (p<0.044). Conclusions: Infectious dermatoses remain as the far most common skin manifestations in HAART naïve patients. Lower the CD4 higher will be the incidence. Rare endemic infections like penicilliosis should be considered in differentials of umbulicated lesions in this part of the country.

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Mucocutaneous manifestations of human immunodeficiency virus (HIV) infection in children in relation to the degree of immunosuppression

Britto

Augustine

2019

Int J Dermatology

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Background Human immunodeficiency virus (HIV) infection in children is becoming a common occurrence. Worldwide, limited studies have been done on the mucocutaneous manifestations in HIV‐positive children. The aim of our study was to analyze the spectrum of mucocutaneous manifestations of pediatric HIV infection and correlate to degree of immunosuppression. Material and methods One hundred and sixty‐five children under 18 years with HIV, who presented to the departments of dermatology and pediatrics, were examined for mucocutaneous manifestations. Patients were classified into four groups of immunodeficiency such as normal, mild, advanced, and severe, based on NACO guidelines of immunosuppression. The most recent CD4 count (within 6 months of study period) was considered. Results One hundred and sixty‐five patients were examined, and skin manifestations were seen in 100 (61%) of them.The highest incidence of mucocutaneous manifestations was in 6–10 age group. Papular pruritic eruptions (PPE) (16%) was the most common condition, with highest prevalence in severe CD4 category (38%). Molluscum contagiosum (MC) (10%) was the most common infectious condition, with highest prevalence in advanced CD4 category (14%). Severe cutaneous adverse reactions (SCAR) caused by nevirapine were seen in three children. The percentage of skin manifestations was highest in the advanced (107%) and severe (100%) CD4 category. There was no significant difference in manifestations between those who were on antiretroviral therapy (ART) and those not. Conclusion The percentage of skin manifestations increased with degree of CD4 depletion. PPE was found to be the hallmark of severe immunosuppression. However, opportunistic infections did not correlate with severity of immunodeficiency.

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A clinico-epidemiological study of dermatoses in pediatric HIV patients in a tertiary care center

Cited by 4 publications

References 0 publications

Clinico-Epidemiological Profile of Viral Sexually Transmitted Infections in Seropositive Patients Attending a Tertiary Care Hospital in North India

Clinico-Epidemiological Profile of Viral Sexually Transmitted Infections in Seropositive Patients Attending a Tertiary Care Hospital in North India

Dermatological manifestations of acquired immunodeficiency syndrome: an observational study among HAART naive patients from an ART centre of excellence

Mucocutaneous manifestations of human immunodeficiency virus (HIV) infection in children in relation to the degree of immunosuppression

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