“…In subsequent decades, the range of treatment methods and fields has been continuously expanded, from PEI to radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation (LA), cryoablation (CA), highintensity focused ultrasound (HIFU), and irreversible electroporation (IRE) [8]. Organs such as the liver, pancreas, kidney, adrenal gland, prostate, uterus, biliary tract, lung, breast, thyroid, and other organs have been treated [9][10][11][12][13][14][15][16][17]. Although surgical resection of HCC remains the gold standard, up to 80% of tumors are nonresectable, and require chemotherapy, radiation therapy and/or interventional locoregional ablative procedures.…”