A clinical study of 32 patients with oral discoid lupus erythematosus

Schiødt, Morten; Halberg, P; Hentzer, B

doi:10.1016/s0300-9785(78)80052-0

Cited by 49 publications

(32 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Peak age of onset is 30 years in females and 40 years in males. [6][7][8][9][10] It is predominantly seen in females in the ratio 3:1 and 3:2 and more severe in blacks. Face, scalp, nose, ears, V area of the neck, and extensor aspect of the arms, any area of the face including the eyebrows, eyelids, nose, and lips can be affected.…”

Section: Discussionmentioning

confidence: 99%

“…Face, scalp, nose, ears, V area of the neck, and extensor aspect of the arms, any area of the face including the eyebrows, eyelids, nose, and lips can be affected. [6][7][8][9][10] Early lesions start as patches of erythema, occasionally with an urticarial component later they become papulosquamous and eventuate in elevated reddish edematous plaques covered with adherent graying scales. The lesions tend to enlarge peripherally and may coalesce to produce bizarre patterns.…”

Section: Discussionmentioning

confidence: 99%

“…Keratotic plugs accumulate in dilated follicles that soon become devoid of hair. [8][9][10] When the adherent scale is lifted from more advanced lesions, keratotic spikes as seen in carpet tacks can appears to be projecting from the under surface of the scale (carpet tack sign or tin tact sign). Color of an active lesion is red whereas burned out or scarred lesions are pink or white.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Discoid lupus erythematosus at the vermilion border of the lip: A rare clinical presentation

Roy¹,

Shankarmurthy²

2015

JMRPS

View full text Add to dashboard Cite

Discoid lupus erythematosus (DLE) is a chronic disease which affects the dermatome which causes scarring, hair loss, and hyperpigmentation changes in the skin. It has an effect on one's quality of life, due to its chronic course. Prognosis can be improved if treatment is initiated as early as possible. The condition can be diagnosed clinically, and histopathology may be required to confirm. DLE lesions turning into squamous cell carcinoma has been reported sparsely and due to inadequate data following the reporting of such lesion, this topic deserves attention. Here is an unusual case of DLE which was seen in a young male patient at the vermilion border of the lip.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Discoid lupus erythematosus at the vermilion border of the lip: A rare clinical presentation

Roy¹,

Shankarmurthy²

2015

JMRPS

View full text Add to dashboard Cite

show abstract

“…These may occur without involvement of skin lesions or before the skin lesions develop. [2] Oral discoid lesions most commonly occur on the labial mucosa, vermillion border and buccal mucosa.…”

Section: Introductionmentioning

confidence: 99%

Oral discoid lupus erythematosus: A study of twenty-one cases

Ranginwala¹,

Chalishazar²,

Panja³

et al. 2012

J Oral Maxillofac Pathol

View full text Add to dashboard Cite

Aims:This study was undertaken to analyze the histopathological findings of oral discoid lupus erythematosus with conventional light microscopy for early diagnosis of the oral lesions that would aid in prompt treatment.Objectives:To find out the predominant age, sex, site and clinical features of oral discoid lupus erythematosus. To study the histopathological features of oral discoid lupus erythematosus. To study the alterations of basement membrane changes of oral discoid lupus erythematosus.Materials and Methods:Our study consisted 21 cases of diagnosed DLE with oral lesions. A detailed clinical proforma was used for thorough clinical examination and light microscopy was used for histopathological study of the incisional biopsy specimens.Statistical Analysis Used:The lesions were diagnosed on the histopathological criteria given by Gisslen et al. and was statistically analyzed using the Chi square test.Results:In the present study 9.52% patients had only oral lesions, while 90.47% patients had oral lesions along with skin lesions with the most common site of oral involvement being labial mucosa (76.19%), vermillion border (71.42%) and buccal mucosa (42.85%). On clinical examination, white spots were present in 28.6%, ulcers in 19% and central erythema in 52.4% lesions. Histopathologically, atrophy was observed in 66.66% cases, acanthosis in 66.66% and acanthosis alternating with atrophy in 33.33% cases along with the basement membrane appearing thin and homogenous in 66.7% and partially destroyed in 81% cases with Periodic Acid Schiff stain.Conclusions:Thus, from this study it was found that a diagnosis of oral discoid lupus erythematosus was based on the combination of clinical and histopathological findings. Thus the dentist may be in an important position to establish the diagnosis with the aid of clinical and histopathological findings before the cutaneous lesions become apparent.

show abstract

“…[1] It is not a specific disease entity, but a gingival response associated with a variety of conditions. [2] These desquamative lesions represent oral manifestations of various dermatoses which include Lichen planus, Pemphigus vulgaris, Erythema multiform, Lupus erythematosus, dermatitis herpetiformis, and chronic ulcerative stomatitis. [3]…”

Section: Introductionmentioning

confidence: 99%

Discoid lupus erythematosus involving gingiva

Kranti

Seshan

Juliet

2012

J Indian Soc Periodontol

View full text Add to dashboard Cite

Desquamative gingival lesions are non-plaque induced inflammatory gingival lesions. It is a clinical description and not a diagnosis. These desquamative lesions represent oral manifestations of various dermatoses. Discoid lupus erythematosus is one of the rare dermatoses which show desquamative lesions as oral manifestations. This article presents a rare case report of discoid lupus erythematosus with oral lesions involving gingiva of a 66-year-old female patient.

show abstract

A clinical study of 32 patients with oral discoid lupus erythematosus

Cited by 49 publications

References 14 publications

Discoid lupus erythematosus at the vermilion border of the lip: A rare clinical presentation

Discoid lupus erythematosus at the vermilion border of the lip: A rare clinical presentation

Oral discoid lupus erythematosus: A study of twenty-one cases

Discoid lupus erythematosus involving gingiva

Contact Info

Product

Resources

About