A Clinical, Mycological, and Immunological Survey for Dermatophytosis

Jones, Henry E.; Reinhardt, Jeffrey H.; Rinaldi, Michael G.

doi:10.1001/archderm.1973.01620220033008

Cited by 111 publications

(31 citation statements)

References 21 publications

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“…4. Candidal onychomycosis involves all the nail plates [7,8,9]. There is true invasion of nail plate by candida albicans resulting in dystrophic nail.…”

Section: Discussionmentioning

confidence: 99%

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A study of nail changes in various dermatosis in Punjab, India

Puri¹,

Kaur²

2012

Our Dermatol Online

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Nails act as a window to diagnosis of skin diseases. Various dermatosis affect the nails and the severity of the skin disorder is reflected in the nails. Nail changes are seen in various dermatosis like psoriasis, lichen planus, onychomycosis, collagen vascular disorders, vescicobullous disorders and other papulosquamous disorders. We will discuss in detail regarding nail changes in various dermatosis. StreszczeniePaznokcie są jak okno w diagnostyce chorób skóry. Różne dermatozy wpływają na paznokcie a ciężkość choroby skóry ma swoje odbicie na stanie paznokci. Zmiany w paznokciach widoczne są w różnych dermatozach takich jak łuszczyca, liszaj płaski, grzybica paznokci, kolagenowa choroba naczyń krwionośnych, zaburzenia pęcherzowe i inne zaburzenia grudkowo-złuszczające. Omówimy szczegółowo zmiany paznokci w różnych dermatozach.

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“…4. Candidal onychomycosis involves all the nail plates [7,8,9]. There is true invasion of nail plate by candida albicans resulting in dystrophic nail.…”

Section: Discussionmentioning

confidence: 99%

“…Genetic disorders: Epidermolysis bullosa, congenital onychodysplasia of index finger, Racket nail, Dolichonychia, ichthyosis, incontinentia-pigmenti, acrodermatitis enteropathica. 9. Cosmetics induced nail changes.…”

Section: Introductionmentioning

confidence: 99%

A study of nail changes in various dermatosis in Punjab, India

Puri¹,

Kaur²

2012

Our Dermatol Online

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“…As early as 1949, a high incidence of allergic history in patients with chronic dermatophytosis was reported (48,61,63). Although elevated total IgE levels in the serum of patients with chronic dermatophytosis have been reported (7), normal IgE levels have also been observed among individuals with athlete's foot, irrespective of atopic history (87).…”

Section: Background: Historical Perspectivementioning

confidence: 99%

Allergy and Dermatophytes

Woodfolk

2005

Clin Microbiol Rev

144

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Tinea pedis (athlete's foot) and onychomycosis (infection of the toenails) caused by the dermatophyte fungus Trichophyton are highly prevalent in adults. Several Trichophyton allergens have been identified based on elicitation of immunoglobulin E antibody-mediated immediate-hypersensitivity (IH) responses. Evidence of an etiologic role for Trichophyton in asthma in some subjects with IH and chronic dermatophytosis is provided by bronchial reactivity to Trichophyton. Improvement of asthma after systemic antifungal treatment corroborates this link. A unique feature of Trichophyton allergens is the ability of the same antigen to elicit delayed-type hypersensitivity (DTH) in individuals who lack IH reactivity. Delayed responses appear to confer protection, while IH responses do not, based on the association with acute versus chronic skin infection. The amino acid sequence identity of Trichophyton allergens with diverse enzyme families supports a dual role for these proteins in fungal pathogenesis and allergic disease. Characterizing the immunologic properties of Trichophyton allergens and defining immune mechanisms which drive dichotomous responses are pivotal to understanding the dermatophyte-allergy relationship. Recent studies have identified DTH-associated major T-cell epitopes which could facilitate the development of peptide vaccines. Characterization of additional molecular targets by using new techniques may aid not only in the eradication of infection but also in the resolution of allergic symptoms

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“…However, if a patient with AD develops a chronic dermatophyte infection, it is often more severe and more difficult to eradicate. The first extensive report about a link between AD and chronic dermatophyte infections was presented by Jones et al (67). They found that 14 (40%) of 25 patients with chronic dermatophyte infections were atopic (AD, asthma, hay fever, or all three).…”

Section: Atopic Dermatitis Dermatophytes and Other Hyphomycetesmentioning

confidence: 99%

Atopic Dermatitis and Fungi

Faergemann

2002

Mycoses

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A Clinical, Mycological, and Immunological Survey for Dermatophytosis

Cited by 111 publications

References 21 publications

A study of nail changes in various dermatosis in Punjab, India

A study of nail changes in various dermatosis in Punjab, India

Allergy and Dermatophytes

Atopic Dermatitis and Fungi

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