A Clinical Correlation Research of the Hoffmann Sign and Neurological Imaging Findings in Cervical Spinal Cord Compression

Cao, Jing; Liu, Yilin; Wang, Yuqiang; Zhao, Liang; Wang, Weidong; Zhang, Min; Wang, Limin

doi:10.1016/j.wneu.2019.04.254

Cited by 5 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Three studies evaluated the relationship between the presence of the Hoffmann sign and cervical pathology in symptomatic patients. [25][26][27] In these studies, patients were considered to have cervical myelopathy if they were referred for complaints related to the cervical spine and had image evidence of cord compression. The control group consisted of individuals who were referred for similar symptoms but had no evidence of cord compression.…”

Section: Results Of Individual Studiesmentioning

confidence: 99%

“…Of the included studies, 55% were prospective 18,20-23,26 and 45% were retrospective. 24,25,27-29 Sensitivity was calculated from 61 studies that reported on the frequency of clinical signs in a cohort of patients with DCM. 10,30-…”

Section: Resultsmentioning

confidence: 99%

“…For KQ1, the search identified eleven studies that discussed the diagnostic accuracy of various clinical signs (Table 4, Figures 2, 3, 4). 18,[20][21][22][23][24][25][26][27][28][29] Sample sizes ranged from 45 to 7629. The most commonly reported clinical signs were Hoffmann (82%), Babinski (45%), hyperreflexia (36%) and inverted supinator sign (36%).…”

Section: Study Selectionmentioning

confidence: 99%

“…Of the included studies, 55% were prospective 18,[20][21][22][23]26 and 45% were retrospective. 24,25,[27][28][29] Sensitivity was calculated from 61 studies that reported on the frequency of clinical signs in a cohort of patients with DCM. 10, For KQ2, the search identified 5 studies that evaluated the association between various clinical signs and disease severity as measured by the JOA (n = 3), 32,35,88 Nurick (n = 2), 20,88 mJOA (n = 1), 36 European Myelopathy Score (EMS) (n = 1), 88 Prolo Score (n = 1) 88 and Cooper Myelopathy Scale (CMS) (n = 1).…”

Section: Study Selectionmentioning

confidence: 99%

“…The QUADAS-2 scoring system was applied to the eleven studies that discussed diagnostic accuracy of various signs and included a control group. The risk of bias was deemed to be low in 4 studies, 18,23,25,26 moderate in 6 [20][21][22]24,27,29 and high in 1. 28…”

Section: Study Selectionmentioning

confidence: 99%

See 4 more Smart Citations

The value of Clinical signs in the diagnosis of Degenerative Cervical Myelopathy - A Systematic review and Meta-analysis

Jiang,

Davies,

Zipser

et al. 2023

Global Spine Journal

View full text Add to dashboard Cite

Study Design Delayed diagnosis of degenerative cervical myelopathy (DCM) is likely due to a combination of its subtle symptoms, incomplete neurological assessments by clinicians and a lack of public and professional awareness. Diagnostic criteria for DCM will likely facilitate earlier referral for definitive management. Objectives This systematic review aims to determine (i) the diagnostic accuracy of various clinical signs and (ii) the association between clinical signs and disease severity in DCM? Methods A search was performed to identify studies on adult patients that evaluated the diagnostic accuracy of a clinical sign used for diagnosing DCM. Studies were also included if they assessed the association between the presence of a clinical sign and disease severity. The QUADAS-2 tool was used to evaluate the risk of bias of individual studies. Results This review identified eleven studies that used a control group to evaluate the diagnostic accuracy of various signs. An additional 61 articles reported on the frequency of clinical signs in a cohort of DCM patients. The most sensitive clinical tests for diagnosing DCM were the Tromner and hyperreflexia, whereas the most specific tests were the Babinski, Tromner, clonus and inverted supinator sign. Five studies evaluated the association between the presence of various clinical signs and disease severity. There was no definite association between Hoffmann sign, Babinski sign or hyperreflexia and disease severity. Conclusion The presence of clinical signs suggesting spinal cord compression should encourage health care professionals to pursue further investigation, such as neuroimaging to either confirm or refute a diagnosis of DCM.

show abstract

Section: Results Of Individual Studiesmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

See 3 more Smart Citations

The value of Clinical signs in the diagnosis of Degenerative Cervical Myelopathy - A Systematic review and Meta-analysis

Jiang,

Davies,

Zipser

et al. 2023

Global Spine Journal

View full text Add to dashboard Cite

show abstract

Predictive effect of cervical spinal cord compression and corresponding segmental paravertebral muscle degeneration on the severity of symptoms in patients with cervical spondylotic myelopathy

et al. 2021

View full text Add to dashboard Cite

Encephalic Symptoms Leading to Diagnosis of Cervical Myelopathy

Bengtsson,

Mabry

2021

JOSPT Cases

View full text Add to dashboard Cite

Background Dizziness is a common symptom with a plethora of etiologies. Diplopia can implicate severe neurologic disease, including cerebral lesions. When patients are referred to physical therapy with a diagnosis of dizziness, thorough clinical reasoning and medical screening are of utmost importance. Case Presentation A 55-year-old woman presented to a physical therapy clinic with primary symptoms of dizziness and diplopia that were reproduced with active and sustained cervical rotation. Additional history included dysarthria and dysphasia. Sensation and upper and lower motor neuron tests were unremarkable. Horizontal and vertical corrective saccades were observed. Suspicion of cervical arterial dysfunction was cleared by her neurologist. Primary symptoms were reproduced with neurodynamic testing, prompting concern for central pathology and referral back to the neurologist. Magnetic resonance imaging revealed cervical cord compression, subsequently treated with cervical fusion. Postoperative physical therapy included neurodynamic techniques. Outcome and Follow-Up Primary symptoms resolved without recurrence over 12 months, and Dizziness Handicap Inventory scores improved significantly. Discussion Cervical myelopathy can severely impact function and quality of life. Differential diagnosis, screening, appropriate referral, and communication with other providers are among physical therapists' primary responsibilities and integral contributions to the interprofessional care team. JOSPT Cases 2021;1(2):87–91. doi:10.2519/josptcases.2021.10048

show abstract

A Clinical Correlation Research of the Hoffmann Sign and Neurological Imaging Findings in Cervical Spinal Cord Compression

Cited by 5 publications

References 10 publications

The value of Clinical signs in the diagnosis of Degenerative Cervical Myelopathy - A Systematic review and Meta-analysis

The value of Clinical signs in the diagnosis of Degenerative Cervical Myelopathy - A Systematic review and Meta-analysis

Predictive effect of cervical spinal cord compression and corresponding segmental paravertebral muscle degeneration on the severity of symptoms in patients with cervical spondylotic myelopathy

Encephalic Symptoms Leading to Diagnosis of Cervical Myelopathy

Contact Info

Product

Resources

About