A chemical and histochemical study of acid phosphatase in the epididymis of normal, castrate and hormone replaced castrate mice

Allen, John M.; Slater, Judith J.

doi:10.1002/ar.1091300408

Cited by 37 publications

(11 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This localization seems consistent with findings reported on epididymides of several other species. For example, Allen & Slater (1958) studied the epididymis of the mouse and found that acid phosphatase concentration was mainly in the Golgi region of the ciliated cells of caput lobe 3. High activity of this enzyme in the Golgi region has also been reported in the middle of the caput epididymidis of the rat (Martan & Risley, 1963) and the proximal of middle segments of the rabbit (Linnetz & Amann, 1968;Moniem & Glover, 1972) and ram (Moniem & Glover, 1972).…”

Section: Discussionmentioning

confidence: 99%

On the regional histology and histochemistry of the epididymis of the camel (Camelus dromedarius)

Tingari¹,

Moniem²

1979

Reproduction

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

On the regional histology and histochemistry of the epididymis of the camel (Camelus dromedarius)

Tingari¹,

Moniem²

1979

Reproduction

View full text Add to dashboard Cite

“…The bulk of the enzyme material is produced in the vasa deferentia and this may be significant in view of the fact that the spermatozoa of the fowl are held in these parts of the genital tract and not in the epididymides as in mammals. Allen & Slater (1957, 1958 showed alkaline-and acid-phosphatase activities in different parts of the extensive epididymal canal of the mouse. They identified several different types of phosphatases, some of which were shown to be dependent on androgen secretion.…”

Section: Discussionmentioning

confidence: 99%

Histochemical Demonstration of Phosphomonoesterase Secretion in the Genital Tract of the Domestic Cock

Pe¹

1962

Reproduction

View full text Add to dashboard Cite

Intense acid-phosphatase activity was found in the distal parts of the cells lining the entire length of the vas deferens of the domestic cock and there was evidence that the enzyme (s) is secreted in large amounts into the seminal plasma. Some acid phosphatase(s) was also produced in the vasa efferentia and seminiferous tubules.Intense alkaline-phosphatase activity was found only in secretions of certain parts of the vasa efferentia, in the tunica intima of all small blood vessels and in intertubular tissue. From the evidence, it is con¬ sidered that some alkaline phosphatase(s) might possibly diffuse into the seminal plasma from all regions of the genital tract, but it is likely to be small in amount. The significance of the presence of phosphomonoesterases in seminal plasma is discussed.

show abstract

“…These observations suggest that there is a rapid cessation of macromolecule production and secretion, a conclusion supported by evidence from long-term studies showing that protein synthesis, and other metabolic processes in the epididymis, are much reduced after castration but can be restored by androgen replacement therapy (Allen & Slater, 1958;Martan, 1969;Hamilton, Jones & Fawcett, 1969;Brooks, 1976).…”

Section: Introductionmentioning

confidence: 70%

Effects of castration on specific glycoprotein secretions of the epididymis in the rabbit and hamster

Moore¹

1981

Reproduction

View full text Add to dashboard Cite

Summary. Mature male rabbits and hamsters were bilaterally castrated and their epididymides were examined, at 2, 4, 7, 9 and 14 days after operation, for the presence of several glycoproteins by using monospecific antisera and indirect immunoperoxidase labelling. In the rabbit, there was a reduction in the glycoprotein reaction product in the epithelium of the proximal caput epididymidis by 2\p=n-\4days after castration, and the staining was weak or absent by 7\p=n-\9 days. Compared with controls, there was also a marked decrease in the intensity of reaction product to glycoprotein in the lumen of the proximal and distal corpus epididymidis 2\p=n-\4 days after castration although spermatozoa still filled the duct in this region. Glycoprotein was present in the distal cauda epididymidis at 14 days but staining diminished as spermatozoa were cleared from the tract. In the hamster, epididymal glycoproteins were apparently less critically dependent on androgens than those in the rabbit, reaching a weak but constant level in the proximal region by 7\p=n-\9 days after castration and remaining at the same intensity in the distal cauda epididymidis throughout the study.These results suggest that the secretion of specific glycoproteins by the mammalian epididymis is related to androgen levels and to sperm maturation.

show abstract

A chemical and histochemical study of acid phosphatase in the epididymis of normal, castrate and hormone replaced castrate mice

Cited by 37 publications

References 10 publications

On the regional histology and histochemistry of the epididymis of the camel (Camelus dromedarius)

On the regional histology and histochemistry of the epididymis of the camel (Camelus dromedarius)

Histochemical Demonstration of Phosphomonoesterase Secretion in the Genital Tract of the Domestic Cock

Effects of castration on specific glycoprotein secretions of the epididymis in the rabbit and hamster

Contact Info

Product

Resources

About