A case study of Plummer-Vinson syndrome

Sinha, Vikas; Prajapati, Bela J.; George, Ajay; Gupta, Devang

doi:10.1007/bf03049607

Cited by 14 publications

(12 citation statements)

References 6 publications

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“…Plummer-Vinson syndrome (PVS) is characterized by dysphagia which is usually due to upper esophageal web, anemia, splenomegaly and other features like angular cheilitis and glossitis [1]. It is also known as Paterson-Kelly syndrome or sideropenic anemia with epithelial lesions.…”

Section: Introductionmentioning

confidence: 99%

Plummer Vinson syndrome in a male and his chromosomal study – A case report

Swain

Panigrahy

Sahu

2015

Egyptian Journal of Medical Human Genetics

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Plummer Vinson syndrome (PVS) is a triad of iron deficiency anemia, esophageal web and dysphagia. The exact etiology of PVS remains controversial but it has been associated with nutritional deficiency, autoimmune disorders, hereditary factors and remarkable high female predominance. This paper reports an atypical presentation of PVS in a 38 year old Indian male with special emphasis given on chromosomal analysis. Chromosomal assessment is done as it is a good predictor of the possibility of development of post-cricoid carcinoma (PCC) in patients with PVS. Chromosomal aberrations like translocation, gain, loss, breakpoints and duplications are studied and they revealed normal male chromosomal pairing. Ó 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of Ain Shams University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Section: Introductionmentioning

confidence: 99%

Plummer Vinson syndrome in a male and his chromosomal study – A case report

Swain

Panigrahy

Sahu

2015

Egyptian Journal of Medical Human Genetics

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“…5 In view of risk for malignant changes in upper gastrointestinal tract, patients require regular follow-up and yearly endoscopic evaluation at least for initial few years after management. [6][7][8] Family history should be sought in such patients to rule out if any other family member was affected.…”

Section: Discussionmentioning

confidence: 99%

Plummer-Vinson syndrome: a case report

2018

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Plummer-Vinson syndrome (PVS) also named as Patterson-Brown-Kelly syndrome is a combined presentation of three things- dysphagia, iron deficiency anemia, and esophageal webs, seen more often in middle aged females. A 30-year-old female presented to us with shortness of breath on exertion and long standing dysphagia and weight loss. After investigations she was found to be severely anemic. Upper GI endoscopy revealed esophageal web. Dilatation of esophageal web was done, anemia was corrected. Patient is on regular follow-up with marked improvement in terms of weight gain and increased functional capacity.

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“…of patients with PVS, and thus it has been suggested that yearly endoscopic controls should be performed for such patients [15,16]. Tissue iron plays a vital role in the propagation of epithelial cells.…”

Section: What Should the Clinician Ask Him/herself Or The Patient? Y mentioning

confidence: 99%

A Rare Case Report on Plummer-Vinson Syndrome with a Complication of Oral Cancer in a South-Asian Woman

Ayisha¹,

Ali²

2020

CMI

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Plummer-Vinson syndrome (PVS), also called "Paterson-Brown-Kelly syndrome“, is a rare medical syndrome generally affecting middle-aged women. Iron deficiency anemia is the prime etiological factor and other probable factors include malnutrition, genetic predisposition, or autoimmune processes characterized by three distinctive features: iron deficiency anemia, dysphagia, and esophageal web. The dysphagia is generally painless and intermittent or progressive over years, restricted to solids, and associated with weight loss. The exact pathogenesis of PVS is still indistinguishable, but it is interconnected with iron deficiency anemia. Plummer-Vinson syndrome, if left untreated, carries an increased risk of developing squamous cell carcinoma of the upper alimentary tract.In this case report, a 40-year-old female patient presented long-standing dysphagia for months, which progressively developed to postcricoid squamous cell carcinoma by the time she approached to medical treatment. Diagnosis was confirmed through laboratory tests, showing iron deficiency anemia and whole-body positron emission tomography-computed tomography (PET-CT) presenting squamous cell carcinoma in postcricoid region (hypopharynx).

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A case study of Plummer-Vinson syndrome

Cited by 14 publications

References 6 publications

Plummer Vinson syndrome in a male and his chromosomal study – A case report

Plummer Vinson syndrome in a male and his chromosomal study – A case report

Plummer-Vinson syndrome: a case report

A Rare Case Report on Plummer-Vinson Syndrome with a Complication of Oral Cancer in a South-Asian Woman

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