A Case Report of a Giant Pheochromocytoma

Abstract

Pheochromocytoma is a rare catecholamine secreting tumor that are usually arise from adrenal medulla and produces signs and symptoms of excessive catecholamine secretion from tumor. A 32 years old female presented to the hospital, with dyspeptic symptoms. She had fluctuative hypertension, palpitation and sweating. Abdominal ultrasonography showed a right adrenal mass, and computed tomography of the adrenal glands confirmed a right adrenal mass. However, clinical biochemistry tests specific for pheochromocytoma was not performed. Laparoscopic right adrenalectomy was done and the adrenal tumor was excised. Histopathology and immunohistochemistry confirmed the diagnosis of adrenal pheochromocytoma; the tumor cells being positive for chromogranin, synaptophysin, S-100 protein, and inhibin. Following the surgery, the patient did well and showed full recovery at follow-up after 1 month.

"Giant Uncomplicated Pheochromocytoma: A Case Report"

“…Pheochromocytomas are not always diagnosed, even when signs of adrenal hormone excess are evident. Approximately 30% of pheochromocytomas are found as incidentalomas, and later accurately diagnosed as pheochromocytomas 7 . Over the last two decades, the incidence of adrenal incidentalomas has dramatically increased because of a widespread use of abdominal imaging modalities, including ultrasound, CT, and magnetic resonance imaging (MRI).…”

“…Over the last two decades, the incidence of adrenal incidentalomas has dramatically increased because of a widespread use of abdominal imaging modalities, including ultrasound, CT, and magnetic resonance imaging (MRI). An understanding of the differential diagnosis of adrenal masses, a biochemical profile of hyperfunctioning adrenal tumours, and assessment of the risk factors for malignancy are required in the evaluation of adrenal incidentalomas 7 . Pheochromocytoma is often referred to as the great mimic, and the differential diagnosis is complex by the very wide range of clinical symptoms reported 8 .…”

Evaluation of Serum Leptin and Ferritin Levels in Children with Major Beta-Thalassemia

“…production, results in persistent immaturity of its hypothalamic-pituitary function (4) . Leptin is a polypeptide hormone with 146 amino acid, this hormone produced by lipocyte in many adipose tissue, which is widely regulate food intake, energy balance, inflammation, lipid metabolism and blood pressure (5) .…”