A case ofAlternaria keratitis treated with fluconazole

Koç, Ayşe; Erkılıç, Kuddusi; Evrensel, Neşe; Çoşkun, Abdulhakim

doi:10.1007/bf01695640

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…4,6,7 Ülkemizden de Alternaria suşlarına bağlı olarak gelişen keratit olgusu bildirilmiştir. 8 Mantar keratitleri için en önemli risk faktörü, bitkisel materyallerle direkt travma olup, sunulan olguda da benzer bir travma öyküsü mevcuttur. 9 Bunun dışında azalan oranlarda geçi-rilmiş oküler cerrahi ve kontakt lens kullanımı da risk faktörleri arasındadır.…”

Section: Discussionunclassified

A Case of Alternaria Alternata Keratitis

Özer¹,

Vatansever²,

Dinç³

et al. 2017

Turkiye Klinikleri J Ophthalmol

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ikrobiyal keratit; korneal lökom, korneal perforasyon, sekonder endoftalmi ve körlük gibi çok ağır komplikasyonlarla sonuçla-nabilen ciddi bir korneal enfeksiyon olup bakteriler, mantarlar veya parazitler nedeni ile ortaya çıkabilmektedir. Ülseratif keratit vakalarının %6-53'ünün mantarlara bağlı olduğu bildirilmiştir.1 Mantar keratitleri sıklıkla travma ile ilişkili olup, genellikle bitkisel materyallerle direkt travma sonucunda ortaya çıkmaktadır. Bu nedenle, daha çok bahçe işi ile uğraşanlarda ve çiftçilerde etken olarak saptanmaktadır. A An na ah ht ta ar r K Ke el li im me el le er r: : Alternaria alternata patotoksin TA; keratit; vorikonazol A AB BS ST TR RA AC CT T A seventy five years old male patient was admitted to clinic with redness, lacrimation and foreign body sensation in his right eye. He had a history of traumatic corneal injury with a plant leaf one month ago. In addition he had no systemic disease and medication history. Best corrected visual acuity was 5/10 in his right eye. On anterior segment examination in the right eye a raised edge lesion was observed at the center of cornea. Corneal scraping was taken from lesion area for microbiological study including fungal cultures. Microbiological examination of corneal scrapings demonstrated the presence of Alternaria alternata and the patient was treated with topical and systemic voriconazole. This is the second reported case of keratitis due to Alternaria spp in our country.

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Section: Discussionunclassified

A Case of Alternaria Alternata Keratitis

Özer¹,

Vatansever²,

Dinç³

et al. 2017

Turkiye Klinikleri J Ophthalmol

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Keratomycosis caused by an Alternaria species

Hsia

Lee

et al. 2002

Ann Ophthalmol

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Alternaria Keratitis: Clinical Presentation and Resolution With Topical Fluconazole or Intrastromal Voriconazole and Topical Caspofungin

2009

Cornea

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Alternaria keratitis has a varied clinical presentation and may present without macroscopic pigmentation. In vitro sensitivity testing may be helpful in directing therapy for Alternaria keratitis, but clinical response should be monitored as the primary endpoint. Response to natamycin was poor, but successful resolution with topical fluconazole or intrastromal voriconazole and topical caspofungin with preservation of good visual acuity was possible.

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A case ofAlternaria keratitis treated with fluconazole

Cited by 6 publications

References 9 publications

A Case of Alternaria Alternata Keratitis

A Case of Alternaria Alternata Keratitis

Keratomycosis caused by an Alternaria species

Alternaria Keratitis: Clinical Presentation and Resolution With Topical Fluconazole or Intrastromal Voriconazole and Topical Caspofungin

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