1989
DOI: 10.1111/j.1600-0560.1989.tb00047.x
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A case of tubular apocrine adenoma with syringocystadenoma papilliferum

Abstract: We report a new case of a Japanese man who developed a tubular apocrine adenoma in association with syringocystadenoma papilliferum. The differences in the histopathological and immunohistochemical findings in these 2 tumors are described. This is the first immunohistochemical study of tubular apocrine adenoma.

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Cited by 39 publications
(16 citation statements)
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“…34,35 Luminal cells are columnar with decapitation secretion, 33 and the tubules are embedded in a fibrotic stroma, 36 2 features that help differentiate them from oncocytomas. They stain similarly to oncocytomas, with luminal cells expressing cytokeratin, 37 Epithelial membrane antigen (EMA), CEA, and GCFDP-15, and peripheral cells expressing S100 protein. 34 They are PAS positive and diastase labile, 33 unlike oncocytomas which are PAS positive and diastase resistant.…”
Section: Discussionmentioning
confidence: 93%
“…34,35 Luminal cells are columnar with decapitation secretion, 33 and the tubules are embedded in a fibrotic stroma, 36 2 features that help differentiate them from oncocytomas. They stain similarly to oncocytomas, with luminal cells expressing cytokeratin, 37 Epithelial membrane antigen (EMA), CEA, and GCFDP-15, and peripheral cells expressing S100 protein. 34 They are PAS positive and diastase labile, 33 unlike oncocytomas which are PAS positive and diastase resistant.…”
Section: Discussionmentioning
confidence: 93%
“…13 Mutations in tumour suppressor gene p16 may contribute to the pathogenesis of SCAP. 53 The tumour is variably denoted to be derived from eccrine, apocrine or apoeccrine origins. 1 2 Histologically, SCAP is a verrucous tumour that displays multiple epithelial invaginations extending down from the epidermis, and contains numerous papillae (fig 8A,B).…”
Section: Scap and Syringocystadenocarcinoma Papilliferummentioning
confidence: 99%
“…Ishiko et al 6 suggested that TAA and SCAP occurred together only when they were preceded by an organoid nevus. Five cases of TAA and SCAP were reported to be associated with NS [4][5][6]8,10 . However, Lee et al 9 reported 1 case in the external auditory canal that had no evidence of pre-existing NS.…”
Section: Discussionmentioning
confidence: 99%