Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands

Abstract

Tumours of cutaneous sweat glands are uncommon, with a wide histological spectrum, complex classification and many different terms often used to describe the same tumour. Furthermore, many eccrine/apocrine lesions coexist within hamartomas or within lesions with composite/mixed differentiation. In addition to the eccrine and apocrine glands, two other skin sweat glands have recently been described: the apoeccrine and the mammary-like glands of the anogenital area. In this review (the second of two articles on skin adnexal neoplasms), common as well as important benign and malignant lesions of cutaneous sweat glands are described, and a summary for differentiating primary adnexal neoplasms from metastatic carcinoma is outlined, striving to maintain a common and acceptable terminology in this complex subject. Composite/mixed adnexal tumours are also discussed briefly.

A Case of Axillar Syringomas

“…Eccrine ducts are widely distributed in the skin. However, syringomas are usually found in the head and neck region, and most often on the eyelids 1 . Less commonly, they can be seen on the scalp, forehead, cheeks, abdomen, extremities, genitalia and buttocks 2 .…”

A Comprehensive Histopathological Study of Skin Appendageal Tumors

“…They are classified into four groups analogous to their appendageal differentiation as follicular, sebaceous, eccrine and apocrine. [5][6][7][8] These tumors generally are benign, but malignant types also exist [9]. A total of 52 appendageal tumours were observed in the current study.…”

Syringomas Treated by Intralesional Insulated Needles without Epidermal Damage

“…They are more common in women than men and represent one of the most common benign neoplasms of the skin. Clinically, syringomas appear as small yellowish or skin-colored papules that are often located on the periorbital areas 1 . Most syringomas involve the facial area, so the cosmetic outcome is important.…”