A Case of Spine Origin Chondroblastoma Metastasis to Lung

Sohn, Se Hoon; Koh, Sung Aee; Kim, Dong Geun; Park, Sung Woo; Lee, Kyung Hee; Kim, Min Kyoung; Choi, Jun Hyuk; Hyun, Myung Soo

doi:10.4143/crt.2009.41.4.241

Cited by 28 publications

(30 citation statements)

References 11 publications

(12 reference statements)

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“…The prognosis of chondroblastoma generally is good, while it is still an aggressive tumor, with risk of local recurrence and extremely rare metastasis [21]. Location, age and persist epiphysis once were considered a possible risk factor for recurrence, while most authors thought inadequate curettage was the most signi cant risk factor associated with local recurrence [4].…”

Section: Discussionmentioning

confidence: 99%

10 Years Follow up of Chondroblastoma Treated with Intralesional Curettage: A Retrospective Study

Yang

Wang

et al. 2020

Preprint

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Introduction: Chondroblastoma is a rare benign tumor mainly occurred in epiphyses and apophyses of long bones, and usually affects the young people. The primary treatment for chondroblastoma is intralesional curettage. The aim of this study was to evaluate the clinical and radiologic results of patients suffering chondroblastoma treated with intralesional curettage, electrocauterization of the cavity and bone grafting. Patients and Methods: From January 2000 to January 2010, 15 patients with chondroblastoma were treated with intralesional curettage and electrocauterization of the cavity, among which14 patients received bone grafting. After operation, patients were immobilized with splint for 4 weeks and followed up for at least 10 years. The recurrence was examined by clinical manifestation and X ray. The clinical outcome included complications and the Musculoskeletal Tumor Society Score (MSTS).Results: Totally, 15 patients with chondroblastoma were enrolled in our study, including 9 males and 6 females, with a mean age of 13 years old (range from 8 to 21 years). The most common chief compliant were pain and limited joint motion, others including local swelling and increased skin temperature. The mean duration of symptom was 5 months (range from 2-14 months). Tumors mostly affected the proximal humerus (7/15), distal femur (4/15), proximal femur (1/15), proximal tibia (2/15) and femoral head (1/15). Eight patients were undiagnosed or misdiagnosed before operation, only 7 patients with a consideration of chondroblastoma. With a mean follow up of 12years (range from 10-16 years) , two patients had complications of upper limb shortening and1 patient suffered re-operation due to tumor recurrence. The mean postoperative MSTS score was 28.1 (range, 24 to 30) points, which was significantly higher than the preoperative score of 17.6 (range, 12 to 21) points.Conclusion: Thorough curettage with electrocauterization and bone grafting has a good functional outcome in the treatment of chondroblastoma, but still has a low risk of recurrence and complications.Level of Evidence: Level IV, retrospective case series.

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Section: Discussionmentioning

confidence: 99%

10 Years Follow up of Chondroblastoma Treated with Intralesional Curettage: A Retrospective Study

Yang

Wang

et al. 2020

Preprint

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“…Pulmonary metastases have been reported even in the cases of chondroblastoma, and these metastases were generally observed after operative managements of the primary lesion [3–5, 9]. An unusual case of chondroblastoma metastasizing in the lung before surgical intervention was previously reported [13]. Although preoperative arterial embolization could be beneficial to prevent further hemorrhage considering the enlarged vessels and hypervascularity of the lesion, tumor embolization was reported to increase the possibility of chondroblastoma metastasis [14].…”

Section: Discussionmentioning

confidence: 99%

A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors

Tonogai

Takahashi

Manabe

et al. 2013

Case Reports in Orthopedics

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Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion in the epiphysis of long bones. We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl. It was difficult to differentiate using imaging information the lesion from malignant bone tumors such as osteosarcoma. Histopathological examination from biopsy proved chondroblastoma. The tumor was resected after preoperative transcatheter embolization. Reconstructive procedure for the proximal humerus was not performed due to the local destruction. The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions and histopathological understandings for this lesion.

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“…The vertebral column is an extremely unusual site of occurrence [4,5,6,7,8,9,10,11,12,13,14,15,16,17]. Ilaslan et al [9] reported 856 chondroblastomas, 9 of which arose in the vertebral column (i.e.…”

Section: Discussionmentioning

confidence: 99%

“…It was first described by Ewing [1] and Codman [2], but it was not until 1942 that Jaffe and Lichtenstein [3] were the first to confirm its chondromatous nature and rightfully name it chondroblastoma. The occurrence of chondroblastoma in the vertebral column is exceptional, with approximately 30 cases reported in the whole spine and less than 10 cases reported within the lumbar region [4,5,6,7,8,9,10,11,12,13,14,15,16]. Brief reports have been published in the literature regarding the diagnostic pitfalls, cytological features, and differential diagnosis of chondroblastoma by aspiration biopsy (AB) [17,18,19,20].…”

Section: Introductionmentioning

confidence: 99%

Chondroblastoma of the Fourth Lumbar Vertebra Diagnosed by Aspiration Biopsy: Case Report and Review of the Literature

Martínez¹,

Núñez

Cortinas³

et al. 2011

Acta Cytologica

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Background: A chondroblastoma is a primary benign bone tumor typically involving the epiphysis of long tubular bones. The occurrence of chondroblastoma in the vertebral column is exceptional. To the best of our knowledge, aspiration biopsy (AB) findings of a lumbar chondroblastoma have only been reported in 1 previous case. Case: A 30-year-old female presented with lower back pain with a duration of 1 month. A CT scan of the 4th lumbar vertebra showed a heterogeneous lytic zone within the body and the right side pedicle surrounded by marginal sclerosis. A CT-fluoroscopy-guided AB was performed and rendered a relatively cellular material with round to oval-shaped cells with a discrete amount of cytoplasm and small nuclei. These cells were distributed in a single-cell manner as well as in groups along with multinucleated osteoclast-like cells. A cytological diagnosis of chondroblastoma was issued. Conclusion: Identification of infrequent benign bone lesions in the vertebral column through AB is a challenge, yet it is of the utmost importance in order to render a correct diagnosis.

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A Case of Spine Origin Chondroblastoma Metastasis to Lung

Cited by 28 publications

References 11 publications

10 Years Follow up of Chondroblastoma Treated with Intralesional Curettage: A Retrospective Study

10 Years Follow up of Chondroblastoma Treated with Intralesional Curettage: A Retrospective Study

A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors

Chondroblastoma of the Fourth Lumbar Vertebra Diagnosed by Aspiration Biopsy: Case Report and Review of the Literature

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