A case of secondary syphilis mimicking palmoplantar psoriasis in HIV infected patient

Bittencourt, Maraya de Jesus Semblano; Brito, Arival Cardoso de; Nascimento, Bianca Angelina Macêdo do; Carvalho, Alessandra Haber; Nascimento, Manoel Dias do

doi:10.1590/abd1806-4841.20153399

Cited by 23 publications

(12 citation statements)

References 8 publications

(14 reference statements)

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“…[4] A case of secondary syphilis mimicking palmoplantar psoriasis has been reported in an HIV patient. [5] In our case, patient had history of unprotected sexual contact with multiple sex workers and history of painless ulcer over glans penis that healed without treatment. Psoriasiform syphilis was suspected, but the biopsy results were consistent with that of psoriasis vulgaris.…”

Section: Discussionmentioning

confidence: 73%

Coexistence of Syphilis and Psoriasis

Kumar¹,

Saradha²,

Anandan³

et al. 2016

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Section: Discussionmentioning

confidence: 73%

Coexistence of Syphilis and Psoriasis

Kumar¹,

Saradha²,

Anandan³

et al. 2016

jemds

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“…There have been case reports of palmoplantar syphilis being mistaken as psoriasis. [910] An interesting feature of our case is the exclusive localization of the pruritic lichenoid lesions on the palms and soles which later evolved into typical lesions of syphilis cornee. Thus, lichenoid histology in palmoplantar lesions needs to be viewed with caution and it warrants a thorough search for other classical features of syphilis such as endothelial swelling and plasma cell infiltration.…”

Section: Discussionmentioning

confidence: 76%

Syphilis cornee mimicking lichen planus clinically and histologically

Ambooken

Asokan

Jisha

et al. 2018

Indian J Sex Transm Dis

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Palmoplantar lesions of secondary syphilis are often termed “syphilis cornee.” A 32-year-old male presented with itchy lichenoid papules on both soles and left palm associated with grayish white papules on the buccal mucosa and glans penis. Initial clinical diagnosis of palmoplantar lichen planus with mucosal involvement was supported by the histopathological finding of interface dermatitis. However, more detailed history, serological tests of syphilis, and review of histopathological findings led us to revise the diagnosis as syphilis cornee. This case highlights the uncommon presentation of syphilis cornee as pruritic palmoplantar lichenoid papules with histology showing interface dermatitis. A high index of clinical suspicion of secondary syphilis is needed as its manifestations are often deceptive.

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“…Secondary syphilis can cause syphilitic keratoderma, which can also result in hyperkeratotic symmetric lesions on the palms and soles. 8 Its histopathology is variable but typically reveals a mononuclear infiltrate extending into the dermis as well as endothelial involvement, including vascular proliferation and swelling. 9 In this case, the changes were confined mainly to the epidermis.…”

Section: Discussionmentioning

confidence: 99%