A case of pulmonary pleomorphic carcinoma metastasizing to the mandibular gingiva

Metastasis of pulmonary adenocarcinoma to the oral cavity: A case report and literatures review of the last 30 years

“…Several studies have recommended palliative treatment (e.g., surgical treatment, chemotherapy, and radiotherapy) to improve the quality of life (QOL) and to maintain the patient's comfort 7,8 . We found 54 cases of oral metastasis of PCs that were reported from 1991 to 2021 in PubMed and Google scholar 9–45 and reviewed these cases, including our case. Kaplan‐Meier survival analyses were performed to determine whether palliative treatment affected overall survival.…”

“…In our review, 41 of 54 patients received palliative treatments, and surgical treatments were common ( n = 10), followed by chemoradiotherapy ( n = 8) (Table 1). 8–44 There were no significant differences in the survival times between patients with and without palliative treatment at 6.49 and 4.36 months, according to the results of the Kaplan‐Meier test (log rank test: P = 0.437, Figure 4), which suggested that palliative treatment had no effect on survival time. Our patient was able to consume food orally using the upper denture after surgical treatment, showing that even if radical therapy cannot be administered, palliative treatment for maintaining oral function may contribute to the improvement of the QOL.…”

Pulmonary pleomorphic carcinoma metastasizing to the anterior mandibular gingiva: A case report and literature review

“…To the best of our knowledge, all cases of metastasis of PPC in oral cavity reported between 1999 and 2014 were from Japan, totaling 10 cases including the present case ( Table 1 ) [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] . These cases show this disease is common in men (8/10 cases), and the metastasis site in oral cavity was posterior teeth gingiva except for the present case.…”

“…PPC is highly malignant, with an intermediate survival time of 10–12 months and a 5-year survival rate of about 10 %. Moreover, only a few cases of metastases to oral cavity from PPC have been reported so far [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] . Although, clinical symptoms of tumor metastases to the oral cavity include pain and tumor, bleeding due to ulceration, it is often diagnosed periodontal diseases or mucosal diseases.…”