A case of primary malignant lymphoma of the uterus

Abstract

Primary uterine non-Hodgkin's lymphoma is a rare malignancy and the most common histological subtype is the diffuse large B-cell lymphoma. This case is a patient underwent surgery for early gastric cancer in November 2007, and determined to be completely cured, and subsequently, during the follow up observation, in pelvic computed tomography, a uterine mass suspicious to be either uterine cervical cancer or uterine sarcoma was observed. She was transferred to department of gynecologic oncology, modified radical hysterectomy and pelvic lymph node dissection were performed. Histologically the uterine mass was diagnosed as diffuse large B-cell lymphoma. Currently she is received the rituximab, cyclophosphamide, adriamycin, vincristine, and prednisone chemotherapy. Thus we report the case with a brief review of the literature. Primary malignant lymphoma in the uterus is very rare, and its diagnosis as well as treatments has not been established. Therefore, in the future, through continuous clinical discussion on this disease, a guideline for the diagnosis and treatment for primary uterine lymphoma should be established.