A case of pityriasis rubra pilaris associated with sacroileitis and autoimmune thyroiditis

Gül, Ülker; Gönül, Müzeyyen; Kılıç, Arzu; Soylu, Seçil; Koçak, Oğuzhan; Gonen, Bosmat; Bodur, Hatice; Güler, Serhat

doi:10.1111/j.1468-3083.2007.02502.x

Cited by 16 publications

(4 citation statements)

References 10 publications

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“…An association between PRP and seronegative arthritis has been reported, with variable clinical features [51–62]. Arthritis can appear before, after, or simultaneously to cutaneous manifestations.…”

Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

“…A highly variable entity, it is further subclassified into six subgroups according to the age of onset, distribution of lesions and clinical course [49,50] (Table 3). An association between PRP and seronegative arthritis has been reported, with variable clinical features [51][52][53][54][55][56][57][58][59][60][61][62]. Arthritis can appear before, after, or simultaneously to cutaneous manifestations.…”

Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

“…Radiographic evidence of acro-osteolysis is frequently described although only two cases of erosive arthritis have been reported [53,59]. Other rheumatological associations with PRP include myositis (specifically dermatomyositis and Wong-type dermatomyositis, with skin lesions characterized by the grouped keratotic follicular papules of PRP) [63,64], autoimmune thyroiditis [60], celiac sprue [65], systemic sclerosis [66] and myasthenia gravis [67].…”

Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

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Beyond plaque psoriasis – pathogenesis and treatment of other psoriasis phenotypes

Iznardo

Puig

2022

Current Opinion in Rheumatology

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Purpose of reviewPsoriasis vulgaris is the commonest presentation of psoriatic disease, but morphologic variants such as pustular psoriasis (PP) and a closely related disease, pityriasis rubra pilaris (PRP), have been known for a long time, have been associated with rheumatologic manifestations indistinguishable from psoriatic arthritis (PsA) that may go unrecognized, and often represent a therapeutic conundrum. There is recent evidence that underlying genetic and pathogenetic differences may provide the basis for newer therapeutic approaches.Recent findingsThis narrative review highlights the clinical, genetic and pathogenetic characteristics of PP and PRP, their association with PsA and recent developments in their treatment, especially with biologic agents targeting IL-36 and other cytokines of pathogenic relevance.SummaryThe clinical manifestations of PP and PRP are less well known to rheumatologists than those of psoriasis, and recent advances in our insight on their pathogenesis may eventually overcome the therapeutic difficulties faced by dermatologists and rheumatologists in the management of these diseases and their rheumatologic manifestations.

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Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

Section: Pityriasis Rubra Pilarismentioning

confidence: 99%

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Beyond plaque psoriasis – pathogenesis and treatment of other psoriasis phenotypes

Iznardo

Puig

2022

Current Opinion in Rheumatology

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“…PRP has been reported in association with HIV infection [11][12][13], malignancy [4] and Down's syndrome [14]. PRP has been reported to occur simultaneously with several autoimmune disorders [7,6,15,16] including thyroiditis [15,16], myositis [17], myasthenia gravis [18], coeliac sprue [19] and vitiligo [14].…”

Section: Discussionmentioning

confidence: 99%

Systemic sclerosis in a patient with pityriasis rubra pilaris

Frikha¹,

Frigui²,

Masmoudi³

et al. 2011

Pan Afr Med Jrnl

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Pityriasis rubra pilaris (PRP) is a rare, chronic erythematous squamous disorder of unknown etiology. It has been found in association with several autoimmune diseases, including thyroiditis, myositis, myasthenia gravis and vitiligo. Herein we report a case of systemic sclerosis in a patient with classic adult pityriasis rubra pilaris. A 38 year old woman with classic adult type 1 pityriasis rubra pilaris (PRP) developed progressive skin thickening of the trunk, face, upper and lower extremities after 2 years of PRP treatment with topical emollients and steroids. Clinical examination and immunological findings were consistent with SSc. Co-existence of these two rare conditions is documented for the first time.

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Pityriasis Rubra Pilaris

Chu

2016

Rook's Textbook of Dermatology, Ninth Edition

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Pityriasis rubra pilaris (PRP) comprises a group of clinically similar papulosquamous dermatoses, the underlying pathogenesis of which is only just beginning to be unravelled. They initially present with erythematous hyperkeratotic perifollicular papules that tend to coalesce into plaques but may progress to erythroderma, particularly in adults. The distribution, age of onset and speed of onset differ markedly between patients and these differences have been used to classify PRP into a number of clinically distinct subtypes. Using candidate gene screening, investigators have identified heterozygous gene mutations in CARD14 , an activator of nuclear factor κ light chain enhancer of activated B cell (NFκB) signalling, which is implicated in other inflammatory diseases. In addition to coverage of conventional therapies such as acitretin and methotrexate, the place of biological agents, in particular ustekinumab, in managing these disorders is discussed.

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A case of pityriasis rubra pilaris associated with sacroileitis and autoimmune thyroiditis

Cited by 16 publications

References 10 publications

Beyond plaque psoriasis – pathogenesis and treatment of other psoriasis phenotypes

Beyond plaque psoriasis – pathogenesis and treatment of other psoriasis phenotypes

Systemic sclerosis in a patient with pityriasis rubra pilaris

Pityriasis Rubra Pilaris

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