“…5,6 The clinical presentation is characterized by pruritic annular erythematous plaques with small vesicles or pustules in a herpetiform pattern. 7 Direct immunofluorescence shows predominantly intercellular binding of IgG, less frequently also deposition of C3, and indirect immunofluorescence microscopy reveals intercellular binding of circulating IgG in the majority of the cases (Figure 1e, f). Dsg-1 is the most commonly detected autoantigen, but antibodies against Dsg-3 and desmocollins have also been observed.…”