A case of pemphigus herpetiformis with excellent response to mycophenolate mofetil

Pemphigus foliaceus transforming into pemphigus herpetiformis

“…5,6 The clinical presentation is characterized by pruritic annular erythematous plaques with small vesicles or pustules in a herpetiform pattern. 7 Direct immunofluorescence shows predominantly intercellular binding of IgG, less frequently also deposition of C3, and indirect immunofluorescence microscopy reveals intercellular binding of circulating IgG in the majority of the cases (Figure 1e, f). Dsg-1 is the most commonly detected autoantigen, but antibodies against Dsg-3 and desmocollins have also been observed.…”

Transformation eines Pemphigus foliaceus in einen Pemphigus herpetiformis

“…5,6 Das klinische Erscheinungsbild ist durch juckende, ringförmige, erythematöse Plaques mit kleinen Bläschen oder Pusteln, angeordnet in einem herpetiformen Muster, gekennzeichnet. 7…”