A Case of Pasteurella haemolytica Sepsis in a Patient with Mitral Valve Disease who Developed a Splenic Abscess

Abstract

We report a patient with sepsis caused by Pasteurella haemolytica, an extremely rare etiologic agent of human infection, who had mitral valve disease and developed a splenic abscess.

Pasteurella (Mannheimia) haemolytica septicemia in an infant: a case report

“…The patient responded well to intravenous cefpirome and had an uneventful recovery. In 2003, Takeda et al reported M. haemolytica sepsis in a 26-year-old male with asymptomatic mitral valve abnormality presenting with fever, pallor, and hepatosplenomegaly [7].…”

“…Reports of such infections are very rare in humans. The first human case of P. haemolytica septicemia with endocarditis was reported in 1963 [4], followed by a case of arterial graft infection [5], a case of bacterial croup [6], and a case of septicemia associated with splenic abscess in 2003 [7]. Recent work published in 1999 on genetic analysis by Angen et al has resulted in a new taxonomic classification for P. haemolytica which was reclassified in a new genus called Mannheimia, family Pasteurellaceae [8].…”

Pasteurellosis as Zoonosis

“…The total number of patients markedly increased in 1990 and 1991 by 39.8% and 24%, respectively, compared to the previous year (6). An increase was also noted in the incidences of Pasteurella gallinarum-induced sepsis developing food poisoning-like symptoms (7) and Pasteurella hemolyticainduced sepsis, which was considered to be splenic abscess (8).…”

Hematogenous pasteurella haemolytica brain abscess

“…Until today, it was reported only in six cases. The first human case was reported in 1962 in a case of septicemia with endocarditis,[6] followed by a case of aortic graft infection in 1994,[7] a case of a respiratory infection in 1998,[8] a case of septicemia in 2003[9] and recently in 2012[1] a case of pneumonia and septicemia in a 7-month-old male from rural area.…”