A case of neuro-Behcet's disease presenting with lumbar spinal cord involvement

Zhao, Bi; Xh, Lai

doi:10.1038/sc.2009.124

Cited by 6 publications

(2 citation statements)

References 4 publications

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“…CSF typically reveals normal glucose, increased protein, and neutrophilic pleocytosis; the IgG index may be elevated, and OCBs are rare. [103][104][105][106]108,117 Acutely, administration of high-dose corticosteroids results in improvement in most patients 103,104,108,110,111,113,119 ; corticosteroid therapy also improved pleocytosis. 117 Infliximab, cyclophosphamide, and intravenous immunoglobulin have been used with some success.…”

Section: Behcet Diseasementioning

confidence: 99%

Transverse Myelitis

et al. 2013

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Transverse myelitis (TM) includes a pathobiologically heterogeneous syndrome characterized by acute or subacute spinal cord dysfunction resulting in paresis, a sensory level, and autonomic (bladder, bowel, and sexual) impairment below the level of the lesion. Etiologies for TM can be broadly classified as parainfectious, paraneoplastic, drug/toxin-induced, systemic autoimmune disorders, and acquired demyelinating diseases. We discuss the clinical evaluation, workup, and acute and long-term management of patients with TM. Additionally, we briefly discuss various disease entities that may cause TM and their salient distinguishing features, as well as disorders that may mimic TM.

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Section: Behcet Diseasementioning

confidence: 99%

Transverse Myelitis

et al. 2013

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“…While uncommon, they must be recognized as nonsurgical entities. 29,75 In fact, in a study of patients treated for spinal cord sarcoidosis, the nonsurgical group had better outcomes than the surgical group. 23 …”

Section: Clinical Vignette: Casementioning

confidence: 99%

Diagnostic pitfalls in spine surgery: masqueraders of surgical spine disease

Walcott¹,

Coumans²,

Kahle³

2011

FOC

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Disorders of the spine are common in clinical medicine, and spine surgery is being performed with increasing frequency in the US. Although many patients with an established diagnosis of a true surgically treatable lesion are referred to a neurosurgeon, the evaluation of patients with spinal disorders can be complex and fraught with diagnostic pitfalls. While “common conditions are common,” astute clinical acumen and vigilance are necessary to identify lesions that masquerade as surgically treatable spine disease that can lead to erroneous diagnosis and treatment. In this review, the authors discuss musculoskeletal, peripheral nerve, metabolic, infectious, inflammatory, and vascular conditions that mimic the syndromes produced by surgical lesions. It is possible that nonsurgical and surgical conditions coexist at times, complicating treatment plans and natural histories. Awareness of these diagnoses can help reduce diagnostic error, thereby avoiding the morbidity and expense associated with an unnecessary operation.

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Behcet’s disease presenting with sudden-onset paraplegia due to anterior spinal artery involvement: 1-year follow-up of rehabilitation in conjunction with medication

et al. 2011

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A 26-year-old male patient with sudden-onset paraplegia was presented. Clinical and imaging evaluation revealed isolated spinal cord lesions at thoracal levels and anterior spinal arterial involvement. Diagnosis of Behcet's disease was established with associating clinical findings with medical history. Vigorous medication and rehabilitation program were performed. Through the 1-year rehabilitation period in conjunction with medication, strength and functions improved gradually. A satisfactory functional gain as a rehabilitative goal in independence in activities of daily living and long-distance ambulation achieved around 4 months. The patient reached full independence after 1-year. As conclusion, Behcet's disease can present with sudden-onset paraplegia. In case of no evident etiology for paraplegia in young male, neuro-Behcet's disease also should be kept in mind. Contrary to assumption, early aggressive treatment and continuous rehabilitation in conjunction with medication might provide good prognosis with excellent clinical outcome in spinal cord involvement. Satisfactory functional recovery should be expected only after 3-4 months, and complete independence can be achieved after 1 year.

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A case of neuro-Behcet's disease presenting with lumbar spinal cord involvement

Cited by 6 publications

References 4 publications

Transverse Myelitis

Transverse Myelitis

Diagnostic pitfalls in spine surgery: masqueraders of surgical spine disease

Behcet’s disease presenting with sudden-onset paraplegia due to anterior spinal artery involvement: 1-year follow-up of rehabilitation in conjunction with medication

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