A case of multiple sclerosis improvement following removal of heavy metal intoxication

Abstract

Multiple sclerosis (MS) is a chronic progressive disease of the central nervous system (CNS) provoking disability and neurological symptoms. The exact causes of SM are unknown, even if it is characterized by focal inflammatory lesions in CNS accompanied by autoimmune reaction against myelin. Indeed, many drugs able to modulate the immune response of patients have been used to treat MS. More recently, toxic metals have been proposed as possible causes of neurodegenerative diseases. The objective of this study is to investigate in vivo the impact of heavy metal intoxication in MS progression. We studied the case of a patient affected by MS, who has been unsuccessfully treated for some years with current therapies. We examined his levels of toxic heavy metals in the urine, following intravenous "challenge" with the chelating agent calcium disodium ethylene diamine tetraacetic acid (EDTA).The patient displayed elevated levels of aluminium, lead and mercury in the urine. Indeed, he was subjected to treatment with EDTA twice a month. Under treatment, the patient revealed in time improved symptoms suggestive of MS remission. The clinical data correlated with the reduction of heavy metal levels in the urine to normal range values. Our case report suggests that levels of toxic metals can be tested in patients affected by neurodegenerative diseases as MS.

Aluminium Involvement in Neurotoxicity

“…We have previously studied the case of a young man affected by MS, who has been unsuccessfully treated for some years with current therapies [29]. Symptoms revealed by the patient were subacute vision loss, diplopia, and pain with eye movements as the first symptoms of optic neuritis; disturbance of fine motor skills; paresthesia and gait ataxia; bladder dysfunction; and significant tiredness.…”

Uses of Complementary and Alternative Medicine in Multiple Sclerosis

“…A study on patients with MS showed that the level of toxic metal in urine reduces after chelation therapies. [1973] Furthermore, chelation therapy can reduce lipid peroxidation and oxidative DNA damage. [69]…”

Improvement of Oxidative and Metabolic Parameters by Cellfood Administration in Patients Affected by Neurodegenerative Diseases on Chelation Treatment

“…Urine collection following chelation treatment lasted 12 hours. Urine samples are accurately enveloped in sterile vials and sent to the Laboratory of Toxicology (Doctor's Data Inc., St. Charles, IL, USA) to be analysed, as previously reported [12]. Briefly, samples are acid-digested with certified metal-free acids (digestion takes place in a closed-vessel microwave digestion system), diluted with ultrapure water, and carried out via inductively coupled plasma with mass spectrometry (ICP-MS) utilizing collision/reaction cell methods coupled with ion-molecule chemistry, a reliable new method for reducing interference.…”

“…Two groups of subjects were studied: 39 patients affected and 11 subjects unaffected by ND (controls). All subjects were affected by chronic body burden of heavy metals and were treated with EDTA to remove metal intoxication [12–14]. The subjects were also daily treated with antioxidant therapy to help the detoxification process: some of them received Cellfood and some other antioxidants [15].…”