A case of multiple leiomyomatous hamartomas on the tongue with palatal recess.

Nishihara, Kazuhide; Nozoe, Etsuro; Mimura, Tamotsu; Marutani, Kazuhiro; Y, Kawagoe; Narita, Makoto; Kitano, Motoo

doi:10.5794/jjoms.37.1506

Cited by 4 publications

(1 citation statement)

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“…There are also reports in the Japanese literature of palatal depression corresponding to the OLH mass in the tongue, suggesting that the mass was present in the period of embryonal development when the secondary palate was formed. 12 Moreover, Falci et al 2 showed an incipient lip cleft that corresponded to an OLH in the anterior maxilla, which probably interfered with the complete fusion of the medial nasal and maxillary prominences. In the same way, an OLH in the dorsum of tongue was associated with bifid tongue tip and ankyloglossia in an adult patient without oral-facial-digital syndrome.…”

Section: Discussionmentioning

confidence: 99%

Leiomyomatous Hamartomas of the Oral Cavity: Clinicopathological and Immunohistochemical Features of 4 Cases and Literature Review

et al. 2019

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Objective. To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review. Methods. The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained from the pathology reports. Microscopical features were reviewed, and immunohistochemical reactions were performed. A review of the English-language literature about OLH was done. Results. The sample was composed of 3 females (4-, 10-, and 15-year-old) and 1 male (3-year-old). Three cases affected the dorsum of the tongue and one the incisive papilla, and all presented sessile or pedunculated smooth nodules. Microscopically, the lesions were composed of varying-size fascicles of smooth muscle fibers in a fibrous connective tissue background. Immunohistochemistry revealed positivity of the smooth muscle bundles for myogenic markers. The English-language literature review revealed 38 OLH cases reported, most were congenital or diagnosed up to 5 years old. The main locations were tongue and anterior maxilla. Conclusions. Although OLH is a rare lesion, it must be considered in the differential diagnosis of midline tongue or maxillary masses in newborns, infants, and youngsters.

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Section: Discussionmentioning

confidence: 99%