A case of lipoatrophic panniculitis in a 2-year-old boy

Weryńska-Kalemba, Maria; Kalemba, Michał; Filipowska-Grońska, Agata; Lorenc, Anna; Jarząb, Jerzy; Bożek, Andrzej

doi:10.5114/ada.2016.59165

Cited by 4 publications

(2 citation statements)

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“…ALA generally presents with an initial inflammatory stage and a late atrophic stage. 4,9,10 The inflammatory phase comprises asymmetrical, 4,9,10 rarely unilateral, 11,12 inflammatory nodules or plaques located on the extremities of the lower limbs (ankles, calves, and feet) and is sometimes associated with debilitating symptoms such as muscle pain and cramps. 6,7,9,10,12,13 Triggers such as upper respiratory tract infection, trauma, and friction are sometimes reported, 4,12,14,15 as was the case for one patient in our series.…”

Section: Discussionmentioning

confidence: 99%

“…Eleven of the 16 cases presented in the literature received treatment: topical 11,19,20 or systemic steroids, 9,11,13,14,16,18,20,22 hydroxychloroquine, 9,14,16 methotrexate, 9,11,14 pentoxifylline, 11 potassium iodide, 22 dapsone, 13 and penicillin. 23 Their efficacy is difficult to assess because of the lack of prospective studies and long-term follow-up.…”

Section: Discussionmentioning

confidence: 99%

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Annular lipoatrophy of the ankle: Four new pediatric cases and a review of the literature

Touhouche

Tournier

Lamant

et al. 2021

Pediatric Dermatology

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Annular lipoatrophy of the ankle (ALA) is a rare acquired lipoatrophic panniculitis first reported in 1953 by Ferreira-Marques by the name lipoatrophia annularis 1 and then described by Winkelmann as connective tissue panniculitis (CTP), 2 but it would appear that ALA is a more localized form of CTP. 3 It mainly affects children who are otherwise healthy but may present with autoimmune diseases 3-5 and has a stereotyped presentation, starting with inflammatory nodules or plaques around the ankles which progress into circumferential subcutaneous atrophy within a few months. There is no consensus on treatment, and long-term outcomes are poorly documented. We present four new cases of childhood ALA, including a patient with an extended follow-up of more than 10 years. | C A S E REP ORTSFour children (two boys and two girls), aged between 5 and 9 years, were diagnosed with ALA. All were otherwise healthy. Their characteristics are presented in Table 1. ALA has a classic history starting with inflammatory nodules or plaques around the ankles and calves evolving over months to subcutaneous atrophy. Some had triggering events, such as Patient 1 (Figure 1) who reported the appearance of lesions after wearing a new pair of high-top shoes that may have caused local trauma. All had a classic history of ALA except for Patient 2, who reported no initial inflammatory stage. Only, Patient 1 reported initial debilitating symptoms (severe cramps and myalgia).The lesions were located on the lower extremities for all patients except for Patient 3 (Figure 2), who had mild lesions on the buttocks.

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