Panniculite lipoatrophiante idiopathique de l’adulte traitée par hydroxychloroquine et autogreffe de cellules graisseuses

Cornille, H.; Adelmand, L.; Garmi, Rachid; Comoz, F.; Verneuil, L.

doi:10.1016/j.annder.2018.07.013

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…In the literature, we found 16 other childhood cases of ALA (Table A1) and four adult female cases (from 19 to 49 years). [5][6][7][8] ALA is a lipoatrophic panniculitis that mostly affects girls (75%). Associated autoimmune diseases have been described (diabetes, celiac disease, thyroid disorders etc.)…”

Section: Discussionmentioning

confidence: 99%

“…In the literature, we found 16 other childhood cases of ALA (Table A1) and four adult female cases (from 19 to 49 years) 5‐8 . ALA is a lipoatrophic panniculitis that mostly affects girls (75%).…”

Section: Discussionmentioning

confidence: 99%

“…Treatment may also play a role in reducing debilitating symptoms, as seen in Patient1, but we cannot exclude the possibility that his cramps may have naturally resolved over the course of the disease. During the stable atrophic phase, the use of reconstructive surgery with autologous fat injection was reported in one child and one adult, with good results 4,8.…”

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confidence: 99%

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Annular lipoatrophy of the ankle: Four new pediatric cases and a review of the literature

Touhouche

Tournier

Lamant

et al. 2021

Pediatric Dermatology

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Annular lipoatrophy of the ankle (ALA) is a rare acquired lipoatrophic panniculitis first reported in 1953 by Ferreira-Marques by the name lipoatrophia annularis 1 and then described by Winkelmann as connective tissue panniculitis (CTP), 2 but it would appear that ALA is a more localized form of CTP. 3 It mainly affects children who are otherwise healthy but may present with autoimmune diseases 3-5 and has a stereotyped presentation, starting with inflammatory nodules or plaques around the ankles which progress into circumferential subcutaneous atrophy within a few months. There is no consensus on treatment, and long-term outcomes are poorly documented. We present four new cases of childhood ALA, including a patient with an extended follow-up of more than 10 years. | C A S E REP ORTSFour children (two boys and two girls), aged between 5 and 9 years, were diagnosed with ALA. All were otherwise healthy. Their characteristics are presented in Table 1. ALA has a classic history starting with inflammatory nodules or plaques around the ankles and calves evolving over months to subcutaneous atrophy. Some had triggering events, such as Patient 1 (Figure 1) who reported the appearance of lesions after wearing a new pair of high-top shoes that may have caused local trauma. All had a classic history of ALA except for Patient 2, who reported no initial inflammatory stage. Only, Patient 1 reported initial debilitating symptoms (severe cramps and myalgia).The lesions were located on the lower extremities for all patients except for Patient 3 (Figure 2), who had mild lesions on the buttocks.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%