A Case of Juvenile Xanthogranuloma Associated with Neurofibromatosis

Kye, Young Chul; Choi, Hyun Chul; Oh, Cheol; Kim, Soon Nam

doi:10.5021/ad.1993.5.1.22

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“…Patients with neurofibromatosis accompanied by juvenile xanthogranuloma showed a 2∼30 times increased risk for leukemia than those with neurofibromatosis alone. Therefore, informing patients with both neurofibromatosis and juvenile xanthogranuloma about the risk is necessary [4][5][6] . Other benign tumors such as granular cell and glomus tumors can also accompany neurofibromatosis 7,8 .…”

Section: Discussionmentioning

confidence: 99%

A Case of Eccrine Spiradenoma in a Patient with Neurofibromatosis

et al. 2010

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Section: Discussionmentioning

confidence: 99%

A Case of Eccrine Spiradenoma in a Patient with Neurofibromatosis

et al. 2010

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Clinicohistopathologic Comparison of Adult Type and Juvenile Type Xanthogranulomas in Korea

Chang

Cho

Choi

et al. 2001

The Journal of Dermatology

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Xanthogranuloma (XG) is an uncommon benign disorder characterized by solitary or multiple yellow-red papulonodules on the skin, and occasionally, in other organs. It is predominantly a disease of infancy or early childhood, although adults may rarely be affected. To compare the clinicohistopathological featues of juvenile-type xanthogranulomas UXGs) and adult-type xanthogranulomas (AXGs) (>14 years) in Korea, 30 cases of JXGs and 15 cases of AXGs were compared clinically and histopathologically. Except for the fact AXGs were more often solitary and larger and showed neither other associated systemic diseases nor spontaneous regression, the clinical features such as color, mean number, or site of the lesions in AXGs were not statistically different from JXGs. Histologically, AXCs were not significantly different in amounts of foamy cells, giant cells including Touton cells, and inflammatory cells, although subcutaneous involvement was seen only in the two infant cases. In conclusion, in contrast to AXGs, JXGs need special attention to accompanying systemic diseases and do not need excisional procedures, considering their frequent spontaneous regression.

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A Case of Juvenile Xanthogranuloma Associated with Neurofibromatosis

Cited by 2 publications

References 0 publications

A Case of Eccrine Spiradenoma in a Patient with Neurofibromatosis

A Case of Eccrine Spiradenoma in a Patient with Neurofibromatosis

Clinicohistopathologic Comparison of Adult Type and Juvenile Type Xanthogranulomas in Korea

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