A case of generalised cutaneous apocrine cystomatosis in a Pekingese dog

Abstract

Clinical, histological and immunohistochemical examination of a 13-year-old male client-owned Pekingese dog revealed an uncommon presentation of apocrine cutaneous cystomatosis. This is a rare non-neoplastic condition of uncertain cause, characterised by multiple cystically dilated apocrine sweat glands. We aimed to describe the features of this unusual case of generalised cutaneous apocrine cystomatosis in the dog, which can be useful to distinguish it from multifocal benign cystic apocrine tumours.

Apocrine cystomatosis: From the aspect of epithelial-mesenchymal transition

“…Cysts are usually localised within the head and neck and are characterised by a group of vesicles measuring up to 3 cm in diameter containing clear, acellular fluid. No sex and breed predisposition have been reported along with its aetiology (Stazi et al 2022). Histopathologically, this condition is characterised by clusters of dilated apocrine glands lined by a layer of cuboidal epithelial cells surrounded by myoepithelial cells (Miller et al 2012).…”

“…Cysts are usually localised within the head and neck and are characterised by a group of vesicles measuring up to 3 cm in diameter containing clear, acellular fluid. No sex and breed predisposition have been reported along with its aetiology ( Stazi et al. 2022 ).…”