A Case of Fungus Ball-Type Pansinusitis Due to Fusarium proliferatum

Hashemi, Seyed Jamal; Ardehali, Mojtaba Mohammadi; Rezaie, Sassan; Zibafar, Ensieh; Shoar, Mohseh Gerami; Rezaei‐Matehkolaei, Ali; Ehteram, Hassan; Najafzadeh, Mohammad Javad; Nazeri, Mehdi

doi:10.1007/s11046-015-9906-1

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…In this paper, we described several very rare cases of F. proliferatum fungus ball maxillary sinusitis. Our cases differed from the first one published by its endodontic origin [5]. Presence of endodontic material in maxillary sinus has been proved to be a risk factor for fungus ball, even if the mechanism still remains unclear.…”

Section: Discussioncontrasting

confidence: 80%

“…Fusarium species, sometimes recovered from other forms of fungal rhinosinusitis such as allergic fungal rhinosinusitis or acute invasive fungal rhinosinusitis, are poorly associated with sinonasal fungus ball. To our knowledge, only one case study reported a fungus ball type pan-sinusitis due to F. proliferatum [5]. Here, we describe two further cases of a fungus ball due to F. proliferatum and provide the first description of this fungal pathogen with a fungus ball of odontogenic origin.…”

Section: Introductionmentioning

confidence: 75%

“…The colony was further identified both by MALDI-TOF mass spectrometry and DNA sequence-based identification as described respectively by Cassagne et al [6] and Gautier et al [7]. The colony was identified as F. proliferatum both by MALDI-TOF mass spectrometry identification (with the interpretation criteria described in [5] and DNA sequence-based identification [>98% identity]). The obtained ITS sequence was blasted against GenBank nucleotide sequences and matched with 100% identity with the F. proliferatum sequence KY425734.1.…”

Section: Microbiological Work-upmentioning

confidence: 99%

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Maxillary fungus balls due to Fusarium proliferatum

Radulesco

Varoquaux

Ranque

et al. 2019

Journal de Mycologie Médicale

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Section: Discussioncontrasting

confidence: 80%

Section: Introductionmentioning

confidence: 75%

Section: Microbiological Work-upmentioning

confidence: 99%

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Maxillary fungus balls due to Fusarium proliferatum

Radulesco

Varoquaux

Ranque

et al. 2019

Journal de Mycologie Médicale

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“…These cases involved two female patients from Iran and two from France, ranging in age from 21 to 68 years, with a mean age of 49.8 years. One patient experienced anosmia ( Hashemi et al., 2015 ), another had esophagitis ( Radulesco et al., 2019 ), while one of them had comorbidities such as coronary artery disease, dyslipidemia, and obesity ( Radulesco et al., 2019 ). Our case had diabetes mellitus, hypertension, heart failure, and anemia.…”

Section: Discussionmentioning

confidence: 99%

Invasive Fusarium rhinosinusitis in COVID-19 patients: report of three cases with successful management

Erami,

Aboutalebian,

Hashemi Hezaveh

et al. 2023

Front. Cell. Infect. Microbiol.

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Invasive fungal rhinosinusitis (IFRS) is a life-threatening infection that can occur in immunocompromised patients, including those with COVID-19. Although Mucorales and Aspergillus species are the most common causes of IFRS, infections caused by other fungi such as Fusarium are rare. In this report, we present three cases of proven rhinosinusitis fusariosis that occurred during or after COVID-19 infection. The diagnosis was confirmed through microscopy, pathology, and culture, and species identification of the isolates was performed by DNA sequencing the entire ITS1-5.8 rRNA-ITS2 region and translation elongation factor 1-alpha (TEF-1α). Antifungal susceptibility testing was conducted according to CLSI guidelines. The causative agents were identified as Fusarium proliferatum, F. oxysporum + Aspergillus flavus, and F. solani/falciforme. Treatment involved the administration of antifungal medication and endoscopic sinus surgery to remove the affected mucosa, leading to the successful resolution of the infections. However, one patient experienced a recurrence of IFRS caused by A. flavus 15 months later. Early diagnosis and timely medical and surgical treatment are crucial in reducing mortality rates associated with invasive fusariosis. Additionally, the cautious use of corticosteroids in COVID-19 patients is highly recommended.

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A Case of Fungus Ball-Type Maxillary Sinusitis Due to Penicillium Roqueforti

et al. 2017

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The Penicillium genera, encompassing about 225 different species of fungi, are naturally present in the environment. These genera are poorly linked to human disease, except for Penicillium marneffei causing septicemia in immunocompromised hosts. Thus, Penicillium species recovered from respiratory tract samples are often considered as inhaled contaminants in the clinical laboratory. However, we report here a case of fungal maxillary sinusitis due to Penicillium roqueforti diagnosed in a 40-year-old female, a teacher, complaining of moderate pain for months in the maxillary sinus and chronic posterior rhinorrhea. CT scanner and MRI enabled a preliminary diagnosis of left maxillary fungus ball-type sinusitis with calcified material seen on CT and marked very low signal in T2 weighted images seen on MRI. Anatomopathological and mycological examination of sinusal content showed septate hyphae. Direct sequencing of the sinusal content revealed P. roqueforti. P. roqueforti has been traditionally used in France for more than 200 years for cheese ripening. However, to our knowledge, this ascomycetous fungus has very rarely been associated in the literature with human disease. P. roqueforti is associated only with cheese worker's lung, a hypersensitivity pneumonitis affecting employees in blue cheese factories. Other species in the Penicillium genus are reported to cause various disorders such as invasive infection, superficial infection or allergic diseases. P. roqueforti has never previously been reported as a cause of human infection. Thus, we report the first case of fungus ball due to P. roqueforti in an immunocompetent patient.

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A Case of Fungus Ball-Type Pansinusitis Due to Fusarium proliferatum

Cited by 6 publications

References 22 publications

Maxillary fungus balls due to Fusarium proliferatum

Maxillary fungus balls due to Fusarium proliferatum

Invasive Fusarium rhinosinusitis in COVID-19 patients: report of three cases with successful management

A Case of Fungus Ball-Type Maxillary Sinusitis Due to Penicillium Roqueforti

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