Maxillary fungus balls due to Fusarium proliferatum

Radulesco, Thomas; Varoquaux, A.; Ranque, Stéphane; Dessi, P.; Michel, J.; Cassagne, Carole

doi:10.1016/j.mycmed.2019.01.008

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…These cases involved two female patients from Iran and two from France, ranging in age from 21 to 68 years, with a mean age of 49.8 years. One patient experienced anosmia ( Hashemi et al., 2015 ), another had esophagitis ( Radulesco et al., 2019 ), while one of them had comorbidities such as coronary artery disease, dyslipidemia, and obesity ( Radulesco et al., 2019 ). Our case had diabetes mellitus, hypertension, heart failure, and anemia.…”

Section: Discussionmentioning

confidence: 99%

Invasive Fusarium rhinosinusitis in COVID-19 patients: report of three cases with successful management

Erami,

Aboutalebian,

Hashemi Hezaveh

et al. 2023

Front. Cell. Infect. Microbiol.

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Invasive fungal rhinosinusitis (IFRS) is a life-threatening infection that can occur in immunocompromised patients, including those with COVID-19. Although Mucorales and Aspergillus species are the most common causes of IFRS, infections caused by other fungi such as Fusarium are rare. In this report, we present three cases of proven rhinosinusitis fusariosis that occurred during or after COVID-19 infection. The diagnosis was confirmed through microscopy, pathology, and culture, and species identification of the isolates was performed by DNA sequencing the entire ITS1-5.8 rRNA-ITS2 region and translation elongation factor 1-alpha (TEF-1α). Antifungal susceptibility testing was conducted according to CLSI guidelines. The causative agents were identified as Fusarium proliferatum, F. oxysporum + Aspergillus flavus, and F. solani/falciforme. Treatment involved the administration of antifungal medication and endoscopic sinus surgery to remove the affected mucosa, leading to the successful resolution of the infections. However, one patient experienced a recurrence of IFRS caused by A. flavus 15 months later. Early diagnosis and timely medical and surgical treatment are crucial in reducing mortality rates associated with invasive fusariosis. Additionally, the cautious use of corticosteroids in COVID-19 patients is highly recommended.

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Section: Discussionmentioning

confidence: 99%

Invasive Fusarium rhinosinusitis in COVID-19 patients: report of three cases with successful management

Erami,

Aboutalebian,

Hashemi Hezaveh

et al. 2023

Front. Cell. Infect. Microbiol.

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“…Two cases of noninvasive fungal rhinosinusitis are described [ 17 ], which developed due to the F. proliferatum disease. They were the first to associate this fungal pathogen with maxillary fungus balls of odontogenic origin [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

A Case of Laying Hens Mycosis Caused by Fusarium proliferatum

Potekhina¹,

Tarasova²,

Matrosova³

et al. 2023

Veterinary Medicine International

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In this article, we present the first case report of a chicken mycosis caused by F. proliferatum occurred on a private farm in the Russian Federation. Lesions on the skin of the legs and scallops were reported. The object of this study was samples of feed and pathological material from sick hens-layers. Mycological analysis included determination of the total number of fungi (TNF) and identification and determination of the toxicity and pathogenicity of the isolates. The identification of the isolate was carried out taking into account direct microscopy, morphological features, and the method of molecular genetic analysis. Microscopic fungi of the genus Penicillium and Rhizopus were isolated by mycological analysis of the feed. The test feed was nontoxic. Mycological examination of pathological material (scrapings from the combs and affected legs) identified an isolate of Fusarium proliferatum, which showed toxicity on biological objects (protozoa, rabbits) and pathogenicity (white mice). Dermal application of F. proliferatum suspension was accompanied by reddening of the rabbit skin. Intraperitoneal injection of fungal spores caused mycosis in white mice. Polymerase chain reaction (PCR) made it possible to identify this type of microscopic fungus (F. proliferatum) with high accuracy in the samples under study. The research results allow us to consider F. proliferatum as a cause of poultry disease against the background of predisposing factors in the form of desquamation of the stratum corneum of the skin against the background of immunosuppression and metabolic disorders caused by an imbalance in the diet.

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