A Case of Fatal Myocarditis Associated with Mycoplasma pneumoniae Pneumonia

Kim, Dae Il; Choi, Jee‐Hye; Cho, Eun Young; Choi, Young June; Sung, Jae Kyu; Yang, Mi Ae; Oh, Chi Eun; Kim, Sohee; Lee, Jun Ho; Lee, Jina; Choi, Eun Hwa; Lee, Hoan Jong

doi:10.14776/kjpid.2009.16.1.92

Cited by 2 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In 1979, Pönkä6) reported that among 560 patients with serologically confirmed M. pneumoniae infection, 25 (4.5%) had carditis (19 perimyocarditis and 6 pericarditis). In contrast, in Korea, only 4 cases of M. pneumoniae -associated pericarditis have been reported in pediatric patients 7-10). Clarithromycin and azithromycin are among the drugs of choice for the treatment of respiratory tract infections.…”

Section: Introductionmentioning

confidence: 99%

“…In contrast, in Korea, only 4 cases of M. pneumoniae -associated pericarditis have been reported in pediatric patients. 7 - 10) Clarithromycin and azithromycin are among the drugs of choice for the treatment of respiratory tract infections. It is important to investigate the association between antibiotic use and resistance as the resistance of common respiratory pathogens to macrolides has been increasing.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Case of Acute Myopericarditis Associated WithMycoplasma PneumoniaeInfection in a Child

Choi

Kim

et al. 2012

Korean Circ J

View full text Add to dashboard Cite

Mycoplasma pneumoniae (M. pneumoniae) primarily causes respiratory tract infections in persons aged 5-20 years. Tracheobronchitis and bronchopneumonia are the most commonly recognized clinical symptoms associated with M. pneumoniae infection. Complications of this infection are unusual; in particular, cardiac involvement is very rare and is generally accompanied by pneumonia. Nonrespiratory illness can therefore involve direct invasion by M. pneumoniae or autoimmune mechanisms, as suggested by the frequency of cross reaction between human antigens and M. pneumoniae. Herein, we report a case of severe acute myopericarditis with pneumonia caused by M. pneumoniae in a healthy young child who presented with fever, lethargy, oliguria and dyspnea. She survived with aggressive therapy including clarithromycin, intravenous immunoglobulin, inotropics, and diuretics. The patient was discharged on the 19th day after admission and followed up 1 month thereafter at the outpatient clinic without sequelae.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case of Acute Myopericarditis Associated WithMycoplasma PneumoniaeInfection in a Child

Choi

Kim

et al. 2012

Korean Circ J

View full text Add to dashboard Cite

show abstract

“…그러나 심근표지 자의 상승은 검사 당시 병의 지속시간과 연관이 있고, 상 승이 나타나지 않은 경우도 있으므로, 정상소견을 보인다 고 해서 심근염을 배제할 수는 없다. 미코플라스마와 심근염의 연관성에 대해 국내에서 사례 보고가 있었다 19) . 미코플라스마의 경우 주로 소아에서 호 흡기 증상으로 발현되어 편도염이나 기관지염, 비전형 폐 렴과 같은 호흡기 질환을 일으키는 것으로 알려져 있으나, 드물게 급성 심근염이나 심막염을 일으키기도 하며, 혈액 검사에서 감염이 확인된 환자에서 1.0-8.5%까지 나타나 는 것으로 보고되고 있다 [20][21][22] .…”

unclassified

A clinical review of acute myocarditis in children

Byun¹,

Lee²,

Lee³

et al. 2015

Pediatr Emerg Med J

View full text Add to dashboard Cite

The aims of this study are to document our single-center experience with pediatric acute myocarditis and to investigate its clinical features and outcomes. Methods: We performed a retrospective chart review of all children aged <16 years who were diagnosed with acute myocarditis between January 2006 and January 2015. We analyzed the following data: initial symptoms, laboratory findings, treatment, and outcomes. We divided patients into two groups according to severity. Results: Twenty-nine patients were diagnosed with acute myocarditis. Thirteen patients (45%) survived to discharge, 4 patients (14%) died, and 12 patients (41%) who required extracorporeal membrane oxygenation were transferred. There was no significant age-related differences in the incidence of myocarditis between children <12 months (45%) and those >12 months (55%) of age. The overall incidence of upper respiratory tract infection symptoms was 69%; general symptoms, 66%; cardiac symptoms, 24%; gastrointestinal symptoms, 17%; and neurologic symptoms, 10%. Twelve patients (41%) had cardiomegaly. Ten patients had electrocardiographic abnormalities (tachycardia, ST changes, T wave changes, and low voltage). Echocardiographic abnormalities were pericardial effusion or impaired contractility. Severe group consisted of 13 patients who were either transferred or died and contained more patients with cardiomegaly and electrocardiogram abnormalities, but this was statistically irrelevant. Most patients had elevated concentrations of cardiac biomarkers, but the median concentrations were not statistically different between the 2 groups. Main treatment modalities included antibiotics (90%), inotropics (59%), and intravenous immunoglobulin (76%). Conclusion: Definite diagnostic criteria for acute myocarditis do not exist, so misdiagnosis can occur. Extracorporeal membrane oxygenation therapy for severe cases is available only in some hospitals, so proper treatment can be delayed. Further evaluation of the current situation regarding acute myocarditis will contribute towards proper treatment.

show abstract

A Case of Fatal Myocarditis Associated with Mycoplasma pneumoniae Pneumonia

Cited by 2 publications

References 9 publications

A Case of Acute Myopericarditis Associated WithMycoplasma PneumoniaeInfection in a Child

A Case of Acute Myopericarditis Associated WithMycoplasma PneumoniaeInfection in a Child

A clinical review of acute myocarditis in children

Contact Info

Product

Resources

About