A case of extensive erosive and bullous erythema elevatum diutinum in a patient diagnosed with human immunodeficiency virus (HIV)

Prabhu, Smitha; Pai, Sathish B; Mohan, Kudur; Sripathi, H; Gupta, Saikat Das

doi:10.1111/j.1365-4632.2010.04616.x

Cited by 10 publications

(8 citation statements)

References 8 publications

(14 reference statements)

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“…[ 10 ] A thorough literature search revealed an association of 20-25 cases of EED with HIV disease. [ 2 3 4 5 6 7 8 9 10 12 ] To the best of our knowledge, our case is the first case of nodular EED simulating Kaposi's sarcoma associated with HIV infection in Indian literature. It is now recognized as one of the defined reactive dermatosis associated with HIV.…”

Section: Discussionmentioning

confidence: 82%

“…[ 4 ] Recently, a case of erosive and bullous EED in HIV-positive patient was also reported. [ 2 ] A rare case of EED with polyclonal gamma-globulinemia with HIV-2 infection was also reported in 1996. [ 12 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] There have been several recent reports of the disease in association with Human Immunodeficiency Virus (HIV). [ 2 3 4 5 6 7 8 ]…”

Section: Introductionmentioning

confidence: 99%

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Nodular erythema elevatum diutinum mimicking Kaposi′s sarcoma in a human immunodeficiency virus infected patient

et al. 2014

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Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times. It is an extremely rare chronic disease of unknown origin and part of the spectrum of leukocytoclastic vasculitis. We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm3. Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

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Nodular erythema elevatum diutinum mimicking Kaposi′s sarcoma in a human immunodeficiency virus infected patient

et al. 2014

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“…[8] Recently, a case of erosive and bullous EED in HIV-positive patient was also reported. [9] It is believed that such an association results from HIV antigen-antibody interaction, which causes direct damage to vessel walls. It is also supposed that the immunosuppression caused by HIV predisposes towards infection by other agents trigger an antigenic stimulus for the development of EED.…”

Section: Discussionmentioning

confidence: 99%

Erythema elevatum diutinum in acquired immune deficiency syndrome: Can it be an immune reconstitution inflammatory syndrome?

Jose

Marfatia

2016

Indian J Sex Transm Dis

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A 47-year-old male with acquired immune deficiency syndrome (AIDS) presented with multiple hyperpigmented papules and nodules on both ankles, dorsum of bilateral feet and soles. It was associated with mild itching and pain. The patient was diagnosed with human immunodeficiency virus (HIV) in 2007. First-line antiretroviral therapy (ART) was started in 2009 to which he responded initially. He was shifted to second-line ART 11 months ago in March 2015 due to treatment failure as suggested by CD4 count of 50 cells/mm3. The present skin lesions started 2 months after the initiation of second-line ART. Differential diagnoses considered were Kaposi's sarcoma and immune reconstitution inflammatory syndrome (IRIS) related infections, but biopsy was suggestive of erythema elevatum diutinum (EED). Patient was started on oral dapsone 100 mg/day and increased to 200 mg/day to which he is responding gradually. In the present case, appearance of the lesions after initiation of second-line ART coupled with increase in CD4 count and decrease of viral load below undetectable level suggest that EED could be an IRIS.

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“…Clinically, it is characterized by symmetrical and persistent papules, plaques, and nodules located on the extensor surfaces of the extremities. 4 …”

Section: Introductionmentioning

confidence: 99%

Clinical and surgical therapeutic approach in Erithema Elevatum Diutinum - case report

Zacaron

Gonçalves

Curty

et al. 2013

An. Bras. Dermatol.

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Erythema elevatum diutinum is a rare chronic cutaneous vasculitis which usually affects adults. It is characterized by symmetrical and persistent papules, plaques, and nodules. These lesions are usually located on the extensor surfaces of the extremities. We report a case of erythema elevatum diutinum in which the association of dapsone and surgical excision promoted complete remission of skin lesions, providing a new approach to the treatments described in the literature.

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A case of extensive erosive and bullous erythema elevatum diutinum in a patient diagnosed with human immunodeficiency virus (HIV)

Cited by 10 publications

References 8 publications

Nodular erythema elevatum diutinum mimicking Kaposi′s sarcoma in a human immunodeficiency virus infected patient

Nodular erythema elevatum diutinum mimicking Kaposi′s sarcoma in a human immunodeficiency virus infected patient

Erythema elevatum diutinum in acquired immune deficiency syndrome: Can it be an immune reconstitution inflammatory syndrome?

Clinical and surgical therapeutic approach in Erithema Elevatum Diutinum - case report

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